Search Homes for Sale

Commercial Real Estate for Sale in Upstate SC

Commercial activity in the Upstate follows the interstates. I-85 between Greenville and Spartanburg carries the industrial and distribution demand, with BMW and its supplier network anchoring most of it; retail and office concentrate around the two downtowns and the Highway 9 and Fairview Road corridors.

Commercial runs on different diligence than residential — zoning and permitted use, environmental history, existing leases and their remaining terms, and what a building can actually be converted to. Tell us what you are trying to do and we will scope the search.

Commercial Listings

$650,000
1574672 MLS
Two functional / like new structures in excellent, well-maintained condition located within a +/-1.89-acre parcel in Cleveland, SC. Take the scenic route to see this beautiful property with breathtaking mountain views and endless possibilities. The 3,355 +/-SF building has four roll-up doors and a double pedestrian door offering versatility for a variety of uses. This former grocery / general store has ample, secure storage, two restrooms and a small kitchen. This building was built for consumer shopping, but with a little creativity and effort it could also be a restaurant, C-store, retail boutique, or breathtaking residence - even an ideal live/work environment. Utilize the +/- 2,875 SF event space in the rear as a restaurant, theater, office, workshop, or event venue. Let your imagination decide how best to utilize the spacious stage bar-type kitchen and a dance floor with surrounding sitting in the building. There is not only steady residential traffic, but this location also enjoys a heavy traffic flow from those visiting Caesars Head State Park and Table Rock State Park. Ideal location for a brewery / tasting room and event space, Great wedding venue or many other uses. Bring your ideas and see this beautiful property today.

4033 Geer Highway, Cleveland
$299,000
4321300 MLS
Zoned HID Unimproved Commercial 0.87 tract only 0.6 miles to I-40 at exit 104 on Old NC 18 across from Broughton Hospital. High traffic Visibility. Wide variety of commercial, business, residential and office uses. (See Zoning permitted uses attached in Disclosures) City utilities & zoning. This location is minutes to main Morganton thorough fare into downtown.

303 Old Nc 18 Highway, Morganton
$2,700,000
4320646 MLS
3213 Westwood Industrial Drive offers an exceptional opportunity for users seeking well-appointed warehouse space with office functionality and excellent regional access. The building totals 18,000 SF, including 1,800 SF of office space and 16,200 SF of warehouse. The warehouse is equipped with two drive-in doors—a 20’ x 20’ oversized door and a 12’ x 12’ door—providing flexible access for a wide range of industrial and distribution needs. Interior features include 16’–20’ clear heights at the eaves, a fully sprinklered system, air compression lines, and heavy-duty power, making it ideal for manufacturing, fabrication, or storage users. Conveniently positioned just off Rocky River Road, the property offers immediate connectivity to Highway 74 and the Monroe Expressway (Bypass), allowing for efficient transportation and distribution throughout the Charlotte region. This functional and well-located facility is a strong fit for tenants seeking high-ceiling warehouse space with quality infrastructure and strategic Monroe access.

3213 Westwood Industrial Drive, Monroe
$2,500,000
4319680 MLS
Versatile combined 3.96-acre property featuring a 1916 home, ideally located just on Highway 521 in a prime, fast-growing area. Ideal for commercial development, mixed-use projects, residential use, or an event venue potential. Close to shopping, dining, schools, and all conveniences, this property offers tremendous potential for investors or entrepreneurs looking to capitalize on one of the region’s most sought-after locations. Combined acreage of 3.96. Currently zoned Low Density Residential. As of 9/26/25 Lancaster County UDO future land use map has it labeled as Growth area meaning Commercial Zoning would be allowed w/Design and Environmental guidelines. County Water available on 521-Contact Lancaster County Water and Sewer as tap fee is required. The Lancaster County 9 month moratorium states it can be subdivided up to 3 parcels. Located in the Southern Panhandle Small Area Plan -https://www.lancastercountysc.gov/251/Southern-Panhandle-Small-Area-Plan Highway 521 is proposed to be widened. Mobile home on property is not habitable. Septic and repair fields on are adjoining property owned by family members, there is no written agreement. There is a buried fuel tank on the property; seller makes no representation as to its condition.

6993 Charlotte Highway, Lancaster
$1,100,000
4319699 MLS
Location, Location. Rare Opportunity to own over1 Acre in Rock Hill's Opportunity Zone. This Provides Investors with tax benefits on capital gains, including full gain elimination if held for at least ten years after redevelopment. Revitalized area is close to a wide range of Business and Communities, with key points of interest including Winthrop University and Rock Hill Sports and Events Center. Road Frontage of 200 feet on White St. Sale includes 6 Lots 203,209,212,215,218 Adams St and 720 W White St. Presently 3 Buildings on Property. Future use has endless possibilities. Business relocating.

218 Adams Street, Rock Hill
$1,800,000
1574433 MLS
*****Prime Investment Opportunity****** +-6.46 Acres total, 6 separate Lots, 4 Homes & a Shop. Unlock the potential of this unique roughly +-6.46-acre investment property offering a rare combination of space, income potential, and flexibility. Situated on six subdivided lots, the property includes four well-maintained homes, a large workshop, and plenty of room for expansion or redevelopment. Each home provides immediate rental income or comfortable living space, while the spacious shop is ideal for business operations, storage, or additional lease income. The multi-lot configuration allows for multiple investment strategies—from long-term rentals and short-term stays to future subdivision or resale. Property Highlights: Total Land: 6.46 acres across 6 separate lots 4 income-producing homes with established utilities 1 versatile shop/building perfect for commercial or personal use Mostly Flat, usable acreage road frontage on Brockman McClimon. Potential for further development or expansion. Ideal for investors, multi-family living, or mixed-use projects This property combines strong current income potential with long-term opportunities—a rare find in today’s market. The 4 homes are currently leased and occupied. 1261 - 4 beds, 2 baths - 1766 sq. ft. 1265 - 3 beds, 2.5 baths - 1705 sq. ft. 1271 - 2 beds with 2 lofts, 1.5 baths - 1150 sq. ft. 1275 - Mobile Home - 3 beds, 2 baths - 1960 sq. ft. Homes share one water tap, separate power, separate septics. Leases to be provided upon offer. 4 Additional lots for sale on 382 Hudson Water that connect.

1261 Brockman Mcclimon Road, Greer
$1,300,000
1574434 MLS
*****Prime Investment Opportunity****** +-3.23 Acres, 4 separate Lots, 2 Homes and two - 1 room apartments. Unlock the potential of this unique roughly +-3.23 -acre investment property offering a rare combination of space, income potential, and flexibility. Situated on four subdivided lots, the property includes two homes, two - 1 room apartments, and plenty of room for expansion or redevelopment. Each home provides immediate rental income or comfortable living space, while the vacant lots are potential development. The multi-lot configuration allows for multiple investment strategies—from long-term rentals and short-term stays to future subdivision or resale. Property Highlights: Total Land: 3.23 acres across 4 separate lots 2 income-producing homes with established utilities 1 vacant lot. Mostly Flat, usable acreage right off highly sought after Brockman McClimon Rd. Potential for further development or expansion. Ideal for investors, multi-family living, or mixed-use projects This property combines strong current income potential with long-term opportunities—a rare find in today’s market. 382 - 3 beds, 2 bath - 1512 sq. ft - Newly renovated. 390 - 3 beds, 2 baths - 1682 sq. ft with 1 room apartment in the back 386 - 1 room apartment 396 - lot only 6 Additional lots for sale at 1261 Brockman McClimon that connect.

382 Hudson Water Road, Greer
$399,900
4320238 MLS
Discover 7.1± acres of prime industrial land zoned I-2, ideally located in western Gastonia on Shannon Bradley Road between Interstate 85 and US Highway 74. This strategic location offers excellent access to major transportation corridors, making it an outstanding site for a variety of industrial or commercial uses. The property features over 300 feet of road frontage on Shannon Bradley Road and has been recently timbered, providing clear and easy viewing of the land’s topography and development potential. City water available; City sewer is close by

001 Shannon Bradley Road, Gastonia
$1,200,000
1574387 MLS
3.63 Acre Commercial Lot at I-85 and US 178/Liberty Hwy Intersection! Desirable high traffic property sits along I-85 and highly traveled Liberty Hwy which is a main thoroughfare between many South Carolina cities including Anderson, Clemson, Pendleton, Central, Easley and Liberty. Site is located along I-85 approximately 125 miles from downtown Atlanta, Ga, 30 miles from downtown Greenville, SC and 125 miles from downtown Charlotte, NC. Parcel is located across from the proposed future location for a Buc-ee's mega convenience store. All utilities, water, gas and three phase electric ready to access your business. Great location for hotel, restaurant, corporate office, shopping plaza, wedding venue and many other business ventures! Seller will subdivide so a possible site for combined businesses. High visibility from I-85 with more than 79,000 combined vehicles passing here each day on I-85 and Hwy 178 (Liberty Hwy) Close to Clemson University, Anderson University, Tri County Technical College and Southern Wesleyan University. Anderson serves 6 Georgia counties for food, entertainment and shopping and is growing at a healthy rate! Nearby properties include beautiful Lake Hartwell, Portman Marina, boat ramps, ,shopping centers, hotels, fast food and dine in restaurants, residential homes and condos. Other large employers include Michelin, Arthrex, Ryobi, Electrolux, First Quality, Walgreens Distribution and many others. Business in close proximity on Liberty Hwy: Vertiv + E&I Engineering USA Corp, Glen Raven Materials Solution, Caliber Collision. Adjacent property across Liberty Hwy is property owned by Buc-ees with plans for a future mega convenience store location. Site is within a mile from Walmart and Sam's Club, Panera's, Texas Roadhouse, Olive Garden, Longhorn, Hardees, Bojangles, Chick Fil-A, Chilis, and more! Huge opportunity at this location! Call for more information and for a 10 page brochure!

Tract 4 Highway 178, Anderson
$1,200,000
20294471 MLS
3.63 Acre Commercial Lot at I-85 and US 178/Liberty Hwy Intersection! Desirable high traffic property sits along I-85 and highly traveled Liberty Hwy which is a main thoroughfare between many South Carolina cities including Anderson, Clemson, Pendleton, Central, Easley and Liberty. Site is located along I-85 approximately 125 miles from downtown Atlanta, Ga, 30 miles from downtown Greenville, SC and 125 miles from downtown Charlotte, NC. All utilities, water, gas and three phase electric ready to access your business. Great location for hotel, restaurant, corporate office, shopping plaza, wedding venue and many other business ventures! Seller will subdivide so a possible site for combined businesses. High visibility from I-85 with more than 79,000 combined vehicles passing here each day on I-85 and Hwy 178 (Liberty Hwy) Close to Clemson University, Anderson University, Tri County Technical College and Southern Wesleyan University. Anderson serves 6 Georgia counties for food, entertainment and shopping and is growing at a healthy rate! Nearby properties include beautiful Lake Hartwell, Portman Marina, boat ramps, ,shopping centers, hotels, fast food and dine in restaurants, residential homes and condos. Other large employers include Michelin, Arthrex, Ryobi, Electrolux, First Quality, Walgreens Distribution and many others. Business in close proximity on Liberty Hwy: Vertiv + E&I Engineering USA Corp, Glen Raven Materials Solution, Caliber Collision. Adjacent property across Liberty Hwy is property owned by Buc-ees with plans for a future mega convenience store location. Site is within a mile from Walmart and Sam's Club, Panera's, Texas Roadhouse, Olive Garden, Longhorn, Hardees, Bojangles, Chick Fil-A, Chilis, and more! Huge opportunity at this location! Call for more information and for a 10 page brochure!

Tract 4 Hwy 178 Highway, Anderson
$1,400,000
4319010 MLS
The Subject is pre-engineering, heavy gauge metal building. Built in 1976 originally, 7500 SQ FT. In 1999, was expanded to its current 11250 SQ FT. Partitioned to 1200 SQ FT. of office and showroom, and 10050 SQ FT warehouse with clear height of 18 ft. Building is 90x125

155 Grayson Road, Rock Hill
$229,900
20294500 MLS
Prime commercial opportunity at the gateway to Walhalla! This high-visibility corner lot sits prominently at the intersection of Highway 28, Earle Street, and E. South Broad Street—complete with a red light and outstanding frontage exposure from all directions. With a high daily traffic count along Highway 28, this property offers exceptional visibility and accessibility for any business venture. City utilities are readily available, including commercial sewer, water, and natural gas, making development straightforward and cost-efficient. Currently zoned Light Industrial, the site can easily be converted to Highway Commercial with city approval, offering flexibility for a wide range of uses. Whether for a restaurant, retail space, storage facility, or investment property, this site is perfectly positioned for growth and long-term success. The owner is also open to a ground lease, presenting additional opportunity for developers or investors seeking a premium location at the entrance to Walhalla.

Corner East South Broad and Earle Street, Walhalla
$399,000
4319598 MLS
Charlotte location, close proximity to Uptown and to I-85 and I-77 corridor. ML-1 zoning is a Manufacturing and Logistics zoning district in Charlotte, NC, intended for light industrial, warehouse, distribution, and light manufacturing and assembly uses. This zoning is designed to accommodate a wide range of industrial activities, and residential uses are generally not permitted in these zones. Purpose: The ML-1 zone is intended for a mix of industrial and logistics uses. Allowed uses: The district allows for a variety of light industrial activities, including assembly, manufacturing, and warehousing/distribution. Prohibited uses: Residential uses are generally prohibited to prevent conflicts with industrial operations.

3555 Northerly Road, Charlotte
$395,000
20294321 MLS
Don't miss this exceptional opportunity to own a +/-0.99-acre flat, graded commercial lot ideally located just off Wells Highway. With excellent visibility and easy access, this versatile property is perfectly positioned in a high-demand area, less than two miles from Prisma Hospital. Whether you're looking to develop office space, retail, medical facilities, or other commercial ventures, this lot offers the ideal foundation. The property’s level terrain and grading significantly reduce development costs, allowing for a smoother and faster build process. The property is also being offered as a ground lease and as a build to suit opportunity. Contact agent for lease terms.

Corner of Wells Hwy. & Return Church Rd. Highway, Seneca
$375,000
4318154 MLS
AMAZING, UNIQUE opportunity to own +/-1.01 acres of land in the heart of desirable Laurel Park!! Lot to be divided off from +/-2.8 acre lot located at 1925 Windsor. See MLS # 4178257 for 2.8 acre lot listing. Friendly "Mountainside Mixed Used" zoning allows for flexible uses, including multiple types of residential and also some commercial!!! All structures convey; however, the home is of no value, and likely needs to be torn down to establish a ROW to this 1.01 acres located at the back (see pictures for suggested location). Roundabout going in on 64. The Ecusta Trail is directly across 64. Photos show nearby points of interest. According to Hendersonville sewer, public sewer is available at Windsor Drive. Work is currently in process at/near this frontage for the expansion on HWY 64.

1925-A Windsor Drive, Laurel Park
$450,000
4318136 MLS
AMAZING, UNIQUE opportunity to own +/-1.4 acres of land in the heart of desirable Laurel Park!! Lot to be divided off from +/-2.8 acre lot located at 1925 Windsor. See MLS # 4178257 for 2.8 acre lot listing. Friendly "Mountainside Mixed Used" zoning allows for flexible uses, including multiple types of residential and also some commercial!!! All structures convey; however, the home is of no value, and likely needs to be torn down. Roundabout going in on 64. The Ecusta Trail is directly across 64. Photos show nearby points of interest. According to Hendersonville sewer, public sewer is available at Windsor Drive. Work is currently in process at/near this frontage for the expansion on HWY 64.

1925-B Windsor Drive, Laurel Park
$2,995,000
4318127 MLS
Introducing an exceptional development opportunity in the heart of Mills River. This MRMU-zoned property offers a strategic foothold for land or industrial investors seeking a presence in the thriving Asheville market. Situated at the intersection of Old Fanning Bridge Road and NC Highway 191, the parcel enjoys nearly 900 feet of frontage on NC 191 with excellent visibility and accessibility. The rectangular configuration, public water access, and gentle topography create a highly developable site suitable for a range of uses. A septic system will be required, but site conditions support straightforward infrastructure planning. With its premier location and versatile development potential, 5620 Old Haywood Road stands out as a compelling investment in one of Western North Carolina’s most desirable commercial corridors. Existing house and barn conveyed at no value. - located at corner of NC 191 and Old Fanning Bridge Rd. - nearly 900 feet of frontage on NC 191 - access to public water (12" and 6" lines) - gentle topography - Town of Mills River - Mixed Use zoning

5620 Old Haywood Road, Mills River
$425,000
2 Baths ⋅ 4311572 MLS
Fantastic commercial opportunity near Uptown Charlotte! This property was previously used as an accounting office and offers excellent visibility and convenience just off Highway 74, near Walmart and other major retailers. The building features multiple flexible-use rooms ideal for professional offices, medical, or service businesses. Ample parking with 7 dedicated spaces provides easy access for clients and staff. Prime location minutes from Uptown, with high traffic and great accessibility — perfect for your growing business!

738 Pierson Drive, Charlotte
$765,000
2 Baths ⋅ 4316706 MLS
For sale, this office/ retail condo offers ±2,329 SF of warm shell space ready for buyer customization and build-out. Previously configured as a medical office, the suite provides a flexible layout ideal for medical, wellness, or professional use. Located in the heart of Asheville’s vibrant River Arts District, just blocks from Mission Hospital, surrounded by restaurants, galleries, and creative businesses, and with easy access to I-240 and I-26, the property combines convenience with character. Highlights include shared parking across Depot Street, street parking in front, and the opportunity to create a modern, efficient office in one of Asheville’s most dynamic and walkable neighborhoods.

408 Depot Street Unit #150, Asheville
$1,790,000
4317317 MLS
Office/Medical Condo #4 Now for Sale in Downtown Hendersonville on N. King St. 5,918+/- SF office space with 18 parking spaces included on the deed and additional on-street parking available. Current Tenant will move out within 12 months. Prime location in the heart of Downtown Hendersonville. Broker Requires 48 hour prior notice to show the unit.

317 N King Street, Hendersonville
$1,399,900
20294103 MLS
2.7 ACRES Pad Ready, Full Access Curb Cut in place Approximately 275' highway frontage All Utilities available Zoned Neighborhood Commercial No Deed Restrictions Strong demographics Great visibility High growth corridor 2024 Traffic Count 19,000 and Rising 2.5 miles to I-85 SALES PRICE $1,399,900

00 N Hwy 81 N Highway, Anderson
$819,000
2 Baths ⋅ 4316577 MLS

704 N Cannon Boulevard, Kannapolis
$2,100,000
4313794 MLS
Prime Development Opportunity: 11.73 Acres with Mountain Views close in to Asheville. Rare offering in one of Asheville's fastest-growing corridors. This 11.73-acre property sits just outside city limits with exceptional access to Patton Ave and I-40, positioning it perfectly for residential or mixed-use development. Property Highlights: 1,200+ feet of road frontage on Holbrook Rd 5 acres of level, cleared pasture ready for development. Stunning mountain ridge views. Two parcels (PINs): 1.57-acre homesite + 10.16-acre pasture 3BR/1BA, 1,226 sq ft rock cottage on-site (vacant Nov 1) Held by same family for 60+ years Development Potential: The cleared, level topography and extensive road frontage offer flexible subdivision possibilities. Combine with the adjacent 21-acre parcel (MLS# 4049531) to create a premier 32.82-acre assemblage with unmatched development upside in this high-demand market. Public utilities nearby.

180 Holbrook Road, Candler
$550,000
20294003 MLS
3.60 acres with 781.71 SF+/- road frontage at Clemson Blvd. and 480.75 SF+/- of road frontage at Wells Highway. Corner property at the traffic light and and sewer availability at Wells Highway across the road. There is a Clemson Blvd. drive way entrance that leads to the former Barber-Shop Building. Level, gentle slope down to the flowing creek that leads to the water fall shoals. Sod grass was being installed and sprinkled from a pump installed at the creek. The brick building has been up-fitted inside into an open shell 1600 SF on the main where new owner can design and the staircase leads 1600 SF in the lower level that has new block pillars, wood-burning brick fire place and walk out door. Close to Clemson University, Lake Keowee, Lake Hartwell, Close to everything ! Buyers to verify everything of importance !

10732 Clemson Boulevard, Seneca
Start Your Search

The Listings data contained on this website comes from various participants of The Multiple Listing Service of Greenville, SC, Inc. Internet Data Exchange. IDX information is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The properties displayed may not be all the properties available. All information provided is deemed reliable but is not guaranteed. © 2026 Greater Greenville Association of REALTORS®. All Rights Reserved. Last Updated

“ Based on information submitted to the MLS GRID as of . All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Some IDX listings have been excluded from this website. Properties may or may not be listed by the office/agent presenting the information © 2026 Canopy MLS as distributed by MLS GRID”

Last Updated: