Search Homes for Sale

Commercial Real Estate for Sale in Upstate SC

Commercial activity in the Upstate follows the interstates. I-85 between Greenville and Spartanburg carries the industrial and distribution demand, with BMW and its supplier network anchoring most of it; retail and office concentrate around the two downtowns and the Highway 9 and Fairview Road corridors.

Commercial runs on different diligence than residential — zoning and permitted use, environmental history, existing leases and their remaining terms, and what a building can actually be converted to. Tell us what you are trying to do and we will scope the search.

Commercial Listings

$200,000
4315976 MLS
This building was a restaurant. The equipment inside will be sold separately.

203 N Cherry Street, Gastonia
$469,000
1 Baths ⋅ 4305810 MLS
A great opportunity for anyone wanting to buy a poultry farm, already operational. J D Covington Poultry Farm is an established two house breeder farm located in Rutherford County, NC The farm currently produces for Case Farms. Barns and approx 18.6 acres have numerous possibilities. Creek runs with property line on back side . The poultry houses are 42X435 and were put into production in 2011. These houses have Cumberland nests with wood slats, Cumberland chain female feeders, Cumberland Male Feeders, Lubing Drinkers, Cumberland conveyer and egg tables. Egg room and large work room in each barn. The farm has 3 working wells on the property. A diesel generator with building. A creek runs along the property line at back part of property. Plenty of beautiful land surrounding the barns and building. Poultry farms are bio-secure facilities. Absolutely no visits to the farm without an appointment.

382 Poole Road, Ellenboro
$550,000
4315488 MLS
Buy 2 commercial building for 1 price!!! Do not miss this good chance!! Retail commercial property for sale. Rare to find this business property in this growing area. 1313 Hwy 9 Bypass property 2175 Sq included. (Currently leased for Antic store). This property runs dry cleaner plant all equipment and inventory will be conveyed. You can have a chance to be an owner of property and business owner.

1317 Hwy 9 W Bypass, Lancaster
$445,000
4313872 MLS
Commercial lot zoned OI behind the old AMC Movie Theater in Rock Hill. The old AMC theater has been redeveloped into Commercial Flex space. Owner is willing to do owner financing with 25% down. Owner can also build to suit your needs if you'd prefer.

2135 Eden Terrace, Rock Hill
$2,125,000
5 Baths ⋅ 1572361 MLS
A 27,000 +/- square feet of industrial building on 50 +/- acres. Two Office spaces 20 x 20 and 35 x 28. 6 bathrooms, 1 loading dock, 3 roll-up doors, and 5 personal doors. Building is 100 x 250 with another 150 feet of length (graded and compacted) ready for expansion if needed. or it could be just covered, whatever fits your needs. Property is located 8 miles from Downtown, 2 miles from Lake Hartwell, and 4 miles from highway 29, 8 miles from Interstate 85 in Anderson County. Property is halfway between Atlanta and Charlotte . Anderson county boasts a healthy business, industrial, and manufacturing climate while having on of the lowest cost of living indexes in the area. Anderson County has harnessed the resources necessary to assist companies in developing a highly skilled workforce. From Lake Hartwell to several Arts and Cultural organizations, Anderson county is a wonderful place to live and raise a family.

5575 Dobbins Bridge Road, Anderson
$849,000
4313348 MLS
Nice brick commercial building currently set up as a medical facility, with a reception area, exam rooms, office areas, room indicator lights, a staff lab, work areas, and more. The building is located in downtown Cherryville in low traffic but in a highly accessible location. The facility is 15 to 20 minutes from Lincolnton, Shelby, Bessemer City, and Dallas; 30 minutes to Gastonia, and within 40 minutes of the Charlotte airport. The building has 12 exam rooms with a hand-wash sink, several private office areas, a room set up for X-ray with a darkroom, two public restrooms, and a private bathroom with a shower, reception area, and waiting room. The building has a private concrete parking lot with approximately 17 spaces, including 2 fully accessible spaces. The rear/side of the building has a delivery and pickup area with a ramp. The facility has been well-maintained and is move-in ready.

112 S Oak Street, Cherryville
$1,900,000
4313314 MLS
Well maintained, free standing commercial building with excess land for potential expansion. High ceilings, abundant parking and separate men's and women’s bathrooms. Village Center zoning is a mixed-use district allowing a multitude of retail, commercial, office and services. Set on Bethel Church Road in Cornelius, NC, 1 block south of Cornelius Road 1 +/- from I-77. Owner will consider sale leaseback. Cornelius, NC is a bedroom suburb of Charlotte with a 1 mile average household income of $170,368 and average house value of $837,167. Catawba Avenue in the vicinity of Bethel Church Road is 25,000 +/- VPD.

19625 Bethel Church Road, Cornelius
$3,950,000
4313050 MLS
Discover the Oriole Mill, over 72,000SF of Highly Adaptive Space, Minutes from Downtown Hendersonville. This two-story facility offers unmatched flexibility for industrial/manufacturing, or adaptive reuse projects. Flexible zoning with versatility within the structure, the site features numerous drive-in doors, dock doors with a full-length loading deck along a formerly active rail spur, and access on all four sides. Located near the Oklawaha Greenway, the property also includes additional land that could be ideal for parking or laydown yard. Whether you're looking to scale operations or reimagine a legacy space, Oriole Mill is a rare opportunity in a rapidly growing market.

701 Oriole Drive, Hendersonville
$799,000
4313029 MLS
Prime Development Opportunity Across from Gardner-Webb University! Discover 23.68 acres of exceptional potential in the heart of Boiling Springs, directly across from Gardner-Webb University. This rare offering features five parcels combining open pastureland and mature wooded areas, providing a beautiful blend of natural scenery and versatility for future development. The property’s highest and best use is residential housing, perfectly suited for a new neighborhood or student housing community, thanks to its unbeatable location near the university, local schools, and town amenities. Included on the property is a home built in 1939 that is currently rented out on a month to month basis—offering immediate rental or on-site living potential while development plans take shape. Opportunities like this are few and far between—whether you’re an investor, developer, or visionary builder, this property offers the space, location, and growth potential to make a lasting impact in Boiling Springs. Don’t miss this unique chance to invest in one of Cleveland County’s most desirable growth areas! Property is also listed as a residential land listing under MLS #4311373

125 Flint Hill Church Road, Shelby
$250,000
4312869 MLS
Commercial parcel in the heart of Kershaw. Directly across from Walgreens. Flat, cleared with water and sewer available. Ready to start your project. 2 parcels together. Corner lot

602/604 Hampton Street, Kershaw
$249,900
2 Baths ⋅ 4311714 MLS
This is a truly unique property offering home and business potential! This former daycare facility was recently renovated to include 3 full residential bathrooms. It can now serve as a comfortable residence while maintaining a layout that is ideally suited for an in-home daycare, preschool, or other care-based business. The floor plan offers multiple spacious rooms that can easily function as bedrooms, playrooms, classrooms, home offices, hobby spaces, or flex rooms to fit your lifestyle. A well-appointed kitchen, dedicated laundry room, and ample storage space provide everyday convenience, while the updated bathrooms make the property move-in ready for residential living. Outside, the possibilities continue with four separate fenced areas that can be used as play spaces, pet areas, gardens, or entertaining spaces. One covered outdoor area provides year-round enjoyment regardless of the weather. The paved parking lot offers plenty of room for family vehicles, guests, or clients, making it ideal for anyone operating a business from home. Situated on a 0.33-acre lot in the heart of Spindale, you'll enjoy the convenience of being within walking distance of downtown Spindale, the Thermal Belt Rail Trail, local restaurants, shopping, and other community amenities. Whether you're searching for a spacious home with incredible flexibility, dreaming of operating an in-home daycare, or looking for a property that allows you to live where you work, this one-of-a-kind opportunity is ready to bring your vision to life!

236 Textile Avenue, Spindale
$199,000
1572030 MLS
Prime retail investment opportunity in the heart of Greenville! This 2,500± sq. ft. building with a metal roof carport sits on 0.45± acres and offers exceptional visibility and access. Located directly off the Augusta Road/I-85 ramp, the property is strategically positioned between I-385 and I-185, and just 4 miles from Downtown Greenville via Augusta Street. The property’s C-2 zoning provides flexibility for a wide range of uses including storage units, auto services, body shops, or parking. Surrounded by strong demographics and high traffic counts, this site is adjacent to two gas stations and conveniently located near Home Depot, offering maximum exposure and steady consumer flow. Additional highlights include visible boundary stakes marking the lot, ample lot size for redevelopment, and proximity to Greenville’s rapidly growing commercial and residential areas. Whether you’re an investor or an owner-user, this location presents an unmatched opportunity to secure a valuable asset in one of Greenville’s most active corridors.

4630 Augusta Road, Greenville
$3,000,000
4310807 MLS
POPLAR LODGE IS NOW FOR SALE!!! Well known for its rustic, mountain retreat feel and stone exterior. The restaurant was a Henderson County landmark known for its dining atmosphere and beloved salad bar. It has the feel of a rustic mountain retreat, with dark logs and creamy chinking. Inside, patrons could enjoy meals around a large fireplace or on the back terrace, all surrounded by mountains. In addition to serving the public, it was a popular venue for meetings, banquets, and special events. In its early years, it functioned as a guest house with a dance hall and nightclub.

2550 Hebron Road, Laurel Park
$1,200,000
4311928 MLS
This commercial building sitting on front corner of 1.34 Acres lot and included next (415 1st St. W.) 0.43 acres land. It's right front of busy street in growing area. You can build your own retail shopping center in the future for rental income. Recently Microsoft company moved in very close to this mixed zoning commercial property includes building and open huge land. Currently one space is tenant occupied operating dry cleaner store and next door is vacant. You can put your own business or rent. One house stands in the back of this building also included to sales price. Bring your offer for future shopping center.

401 1st W Street Unit #1-7, Conover
$999,000
2 Baths ⋅ 1571917 MLS
FOR SALE | FLEX INDUSTRIAL / COMMERCIAL PROPERTY Donaldson Center Area | Greenville, SC Exceptional Opportunity in a Prime Industrial Corridor! Discover this versatile 8,550± SF commercial/industrial building situated on a 0.69-acre lot in the highly desirable Donaldson Center area of Greenville. This well-maintained property offers tremendous flexibility for a range of uses including light manufacturing, warehousing, distribution, or service operations. Conveniently positioned just minutes from I-85, I-185, and Greenville-Spartanburg International Airport, the location provides outstanding regional connectivity—ideal for logistics, operations, or any business seeking strategic access to Upstate South Carolina’s growing industrial network. Property Highlights Total Building Size: 8,550± SF Lot Size: 0.69± acres Zoning: Suitable for light industrial or commercial use Offices: 4 private offices plus a welcoming reception area Restrooms: 2 Warehouse / Manufacturing Space: 7,200± SF of open, flexible layout Access: Roll-up doors and convenient drive-in access Power: 3-phase electrical service – ideal for manufacturing and equipment needs Climate Control: Fully heated and cooled throughout entire building Technology: Wired with Internet and Intranet throughout Security: Alarm system with cameras included Parking: Ample on-site parking with room for expansion or outdoor storage Ideal For Owner-users seeking a move-in-ready industrial space Investors looking for a high-demand flex property in Greenville’s growth corridor Businesses needing a clean, efficient, and well-equipped operations hub Don’t miss this rare opportunity to secure a quality facility in one of Greenville’s most accessible and expanding industrial areas. Location: Donaldson Center Area, Greenville, SC Building Size: 8,550± SF Lot Size: 0.69± acres

7 Akron Drive, Greenville
$2,000,000
4310813 MLS
LOCATION, LOCATION, LOCATION!!! MAIN STREET in Hendersonville 18000 sq ft building on Main Street in Hendersonville. 2000 sq ft is leased and the other 16000 sq ft is ready for upfit. 6000 sq ft on main floor (2000 sq ft is leased) 6000 sq ft on top floor and 6000 sq ft in basement. Could be used for commercial purposes or condos with approval.

201 N Main Street, Hendersonville
$599,900
4311475 MLS
This fabulous building has been extensively updated inside and out and is in immaculate condition. The roof was replaced in 2012-2013 per the seller. The current tenant is interested in continuing use and occupancy after the sale. Alternatively, you could run your business on the lower level and convert the upper level into your living space. The property offers numerous opportunities! Previously used as a workout facility, the upstairs includes a spacious room with mirrored walls, showers, bathrooms, and more. The lower level currently serves as a martial arts studio, complete with restrooms, several side storage rooms, and an office area. The building is exceptionally clean and well-maintained. Come take a look!

109 N Main Avenue, Newton
$550,000
4309161 MLS
Unlock the potential of this exceptional investment opportunity in the heart of downtown Columbus! Situated on a prominent corner along Mills Street, this commercial building features three fully occupied storefronts, each with established tenants generating immediate cash flow. Set on a level, fenced lot, the property offers not only stability but also room for future growth or redevelopment. Whether you’re looking to expand the existing structure, enhance the tenant mix, or hold as a long-term income-producing asset, this property delivers flexibility. Don’t miss your chance to own a solid commercial asset in downtown Columbus. Schedule your tour today and explore the possibilities on Mills Street!

40 E Mills Street, Columbus
$595,000
4308993 MLS
3.49 AC± Off Exit 49B on I-77 in Statesville, Zoned B5 General Business. A prime real estate opportunity for your business. This versatile property is now available for purchase and is ideally suited for a wide range of business operations, including Automotive and Equipment; Auto Rental, Sales, and Service; Boat, Motorcycle, and Trailer Sales and Service; Large Equipment, Farm, Heavy Equipment Sales and Rental; Manufactured/Mobile Home and RV Sales. With off-street parking, this location offers excellent accessibility and visibility, making it a lucrative spot for businesses looking to attract significant traffic and attention. Whether you are an established company or a growing enterprise, this commercial property offers an exceptional opportunity to develop your business in the heart of Statesville’s thriving commercial hub!

Wall Street, Statesville
$1,900,000
1571428 MLS
Location, location, location! Exciting development opportunity in the heart of Woodruff, an up-and-coming area just 20 minutes from Greenville and Spartanburg. Award-winning District 4 Schools, including the new Woodruff High School, are within a mile. Nearby industries include the BMW Battery Plant. This 30-acre parcel is ready for development, currently zoned in the county. Water is available, and sewer is in neighborhood next door. The property includes two tax map IDs: 4-41-00-026.00 and 4-41-00-026.05, with a power line easement.

228 Varner Road, Woodruff
$1,100,000
6 Baths ⋅ 4309816 MLS
Excellent downtown Asheville investment: 58 Broadway St offers 3,531 SF of finished mixed-use space plus a 1,697 SF unfinished basement. The first floor includes a ~400 SF commercial storefront (with mini-split HVAC and its own bathroom) flanked by two apartment units; the second floor houses three additional one-bath apartments, each outfitted with electric heat, electric range, and refrigerator (no central AC). The building is zoned CBD and serviced by city water and sewer. Strategically located on Broadway Street, which sees approximately 10,000 vehicles per day, the property sits just under a mile from I-240 (Exit 1B / Brevard Rd) and within minutes of the I-26/I-240 interchange, offering seamless access to the region’s interstate network. From this address, residents and tenants can walk to dozens of downtown shops, restaurants, and cultural venues, while vehicles can reach Patton Avenue and Charlotte Street in moments. This property is ideal for an owner-user, rental investor, or owner-operator seeking excellent downtown exposure and connectivity.

58 Broadway Street, Asheville
$1,375,000
4309818 MLS
Premier OPPORTUNITY ZONE transit-oriented development site positioned just three blocks from Uptown Charlotte and steps from both the 9th Street and Parkwood CityLYNX Gold Line stations, with walkable access to the LYNX Blue Line. This 0.47-acre ML-2 zoned assemblage at 1113, 1125, and 1127 North Tryon Street offers outstanding visibility, a full signalized intersection, and very strong traffic counts, creating exceptional access and exposure for a future mixed-use, multifamily, office, medical, or retail project. The property sits within the City’s North Tryon Vision Plan, a 60-acre public-private revitalization initiative driving walkability and urban placemaking, and is surrounded by transformative investments, including the $600M Seventh & Tryon redevelopment that will deliver a new central library, office tower, retail, and civic plaza. Only eleven blocks from Bank of America’s headquarters and Uptown’s core employment, cultural, and entertainment districts, this site provides developers and investors a rare opportunity to deliver a signature project at the leading edge of Charlotte’s North Tryon corridor.

1113 N Tryon Street, Charlotte
$825,000
1571330 MLS
EXECUTIVE SUMMARY 4341 Hwy 24 in Anderson, SC is a 1.14-acre parcel with a 5,000 sq ft industrial building, featuring 3-phase electrical power and an above-ground oil tank. Located in a growing area near Hartwell Lake and Anderson Airport, it offers potential for expansion and is in a prime location that is seeing increased development, with a new Circle K being built nearby. This property is also located in an unincorporated area of Anderson County and is zoned C-2, or Highway Commercial District. This zoning designation is suitable for commercial development along a major road. Permitted uses in C-2 zoning The C-2 zoning district allows for a variety of commercial uses. • Existing use: The current use as an auto repair shop is consistent with this zoning. • Commercial uses: The Highway Commercial designation permits a broad range of other business activities, aligning with the commercial growth observed along Hwy 24. Location and Development • Proximity: The property is close to Hartwell Lake and the Anderson Airport. • Growing Area: The area around Highway 24 is experiencing significant growth and development. • Commercial Nearby: A new Circle K convenience store is being built nearby, indicating increased commercial activity. • Future Potential: The property is seen as having potential for further building and development, with the potential to become a "new Clemson Blvd."

4341 S Carolina 24 Highway, Anderson
$189,900
4308377 MLS
High traffic location being used as office space, tanning beds & tattoo parlor. 5 offices, storage room lobby/waiting room, kitchen, nice size bath room, updated central heat & air, fenced back lot, 2 large storage buildings. Sellers using for yard sales. Great parking.

1437 Tryon Courthouse Road, Bessemer City
Start Your Search

The Listings data contained on this website comes from various participants of The Multiple Listing Service of Greenville, SC, Inc. Internet Data Exchange. IDX information is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The properties displayed may not be all the properties available. All information provided is deemed reliable but is not guaranteed. © 2026 Greater Greenville Association of REALTORS®. All Rights Reserved. Last Updated

“ Based on information submitted to the MLS GRID as of . All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Some IDX listings have been excluded from this website. Properties may or may not be listed by the office/agent presenting the information © 2026 Canopy MLS as distributed by MLS GRID”

Last Updated: