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Commercial Real Estate for Sale in Upstate SC

Commercial activity in the Upstate follows the interstates. I-85 between Greenville and Spartanburg carries the industrial and distribution demand, with BMW and its supplier network anchoring most of it; retail and office concentrate around the two downtowns and the Highway 9 and Fairview Road corridors.

Commercial runs on different diligence than residential — zoning and permitted use, environmental history, existing leases and their remaining terms, and what a building can actually be converted to. Tell us what you are trying to do and we will scope the search.

Commercial Listings

$350,000
20300473 MLS
High-Visibility Commercial Property on Highway 28 offering excellent exposure and steady traffic flow in a highly accessible location just minutes from downtown Walhalla and West Union, and approximately 6 miles from Seneca. This commercial building was fully gutted and remodeled in 2020 and now presents a modern, updated space throughout. Improvements include a new roof, HVAC system, water heater, and toilet, along with refreshed interior finishes that create a clean, professional environment. The property offers approximately 1,100 square feet of flexible space suitable for a variety of business uses. Exterior features include wood shutters and window flower boxes that add character and curb appeal, along with custom UV-protected windows, a metal roof, and a slab foundation designed for durability and low maintenance. The interior layout consists of a large open main area, one private office, an additional room with a sink, and one restroom, providing flexibility for professional office, medical, retail, or service-based operations. The property benefits from an average daily traffic count of approximately 15,400 vehicles according to the South Carolina Department of Transportation (2025), offering strong visibility along a well-traveled corridor. Additional features include a front handicap-accessible entrance, a secondary rear access point for staff or deliveries, and approximately 10 on-site parking spaces. Offering is for real estate only; no business, equipment, or operational assets are included in the sale. Well-suited for professional office, medical, administrative, or specialty commercial use in a growing Upstate corridor.

101 Misty Lane, West Union

$2,400,000
4368284 MLS
Introducing a rare 10.61-acre development opportunity in the heart of West Asheville—ideally suited for affordable and workforce housing in one of the region’s most supply-constrained and high-demand submarkets. Located within walking distance of Carrier Park, the Wilma Dykeman Greenway—offering direct access to the River Arts District— as well as essential services, transit corridors, and neighborhood amenities along Haywood Road. This site offers the connectivity and livability critical to successful affordable housing communities. As one of the largest remaining undeveloped tracts in West Asheville, the property offers a unique opportunity to deliver much-needed housing at scale in an area where attainable options are increasingly limited. Conditionally Zoned RM-16 (CZ 08-51-010), the site is entitled under Conditional Zoning Ordinance #3682 (City of Asheville, 2008), allowing for up to 140 multifamily units. Existing entitlements and a prior site plan provide a meaningful head start, helping reduce entitlement risk and accelerate development timelines—key advantages for projects utilizing LIHTC or other funding sources. The site’s natural features, including a small creek and generous open space, create opportunities to incorporate green space, pedestrian connectivity, and community-oriented design elements that enhance resident well-being while aligning with modern affordable housing standards. Comprised of seven contiguous parcels, the property offers multiple access points via State Street, Short Michigan Avenue, and Amboy Road, allowing for flexible site planning and phased development. All major utilities are available at the site, enabling efficient, cost-effective construction. With sustained demand for affordable housing, strong municipal support for attainable development, and limited land availability in West Asheville, this offering presents a compelling opportunity for developers, housing authorities, and mission-driven investors to create a high-impact community while leveraging existing entitlements and infrastructure to accelerate execution. Please contact Listing Agent for all showings. Also listed at MLS# 4370709

99999 State Street, Asheville

$750,000
3 Baths 4364767 MLS
A rare opportunity to breathe new life into a piece of local history. With its size, history, and flexible zoning, this is a truly one-of-a-kind offering in today’s market. Situated on more than 5 fully fenced acres in northern Iredell County, this former schoolhouse offers nearly 22,000 square feet of character, scale, and untapped potential. Opportunities like this rarely come available — and for the right buyer, the possibilities are truly extraordinary. The original main building features approximately 7,900 square feet of heated and cooled space, highlighted by 12-foot ceilings, grand archways, and beautifully preserved maple hardwood floors that reflect the craftsmanship of another era. The roof covering this portion, along with the attached gymnasium/auditorium, was replaced approximately seven years ago. Beyond the main structure, an additional 14,000 square feet of masonry and steel construction provides a substantial and durable footprint ready for restoration, redevelopment, or adaptive reuse. While portions will require roof replacement and improvements, the underlying structure offers a strong and compelling foundation for transformation. The grounds are fully fenced with two large access gates, offering both privacy and flexibility for a wide range of future uses. Zoned Residential Agricultural (RA), the possibilities are expansive and may include: Bed & breakfast or retreat center Wedding or event venue Church or private school Daycare or community center Agricultural or residential development Cluster subdivision or mobile home park For developers, investors, entrepreneurs, or creatives with vision, this is a blank canvas with history, scale, and exceptional potential. Bring your imagination — and write the next chapter of this remarkable property.

1318 Ostwalt Amity Road, Cleveland

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The Listings data contained on this website comes from various participants of The Multiple Listing Service of Greenville, SC, Inc. Internet Data Exchange. IDX information is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The properties displayed may not be all the properties available. All information provided is deemed reliable but is not guaranteed. © 2026 Greater Greenville Association of REALTORS®. All Rights Reserved. Last Updated

“ Based on information submitted to the MLS GRID as of . All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Some IDX listings have been excluded from this website. Properties may or may not be listed by the office/agent presenting the information © 2026 Canopy MLS as distributed by MLS GRID”

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