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Commercial Real Estate for Sale in Upstate SC

Commercial activity in the Upstate follows the interstates. I-85 between Greenville and Spartanburg carries the industrial and distribution demand, with BMW and its supplier network anchoring most of it; retail and office concentrate around the two downtowns and the Highway 9 and Fairview Road corridors.

Commercial runs on different diligence than residential — zoning and permitted use, environmental history, existing leases and their remaining terms, and what a building can actually be converted to. Tell us what you are trying to do and we will scope the search.

Commercial Listings

$800,000
4379737 MLS
Located in the rapidly growing York and Clover corridor, this 1.43 acre commercial property offers a strong combination of location, flexibility, and visibility along busy Filbert Highway. The building contains approximately 1,960 heated square feet and is divided into two separate suites, each featuring its own entrance and restroom, making it ideal for multiple tenants, owner occupancy with additional rental income, or a variety of business uses. The property is zoned General Commercial (GC) through York County and has seen recent exterior improvements including architectural shingles and oversized 6-inch gutters. Positioned only about one mile from QuikTrip, Dollar General, and additional expanding commercial growth in the area, this property is surrounded by increasing activity and continued investment throughout the corridor.

1535 Filbert Highway, York
$5,500,000
4359264 MLS
42 Furman Avenue represents one of the most compelling short-term rental investment opportunities in downtown Asheville—a fully licensed, purpose-built 16-unit STR asset in a market where new permits are no longer issued. Spanning approximately 8,395 square feet across three stories plus a walkout basement, the building was completely renovated to the studs and redesigned specifically for short-term rental use, delivering modern interiors, efficient layouts, and strong visual appeal for today’s guest expectations. The unit mix includes twelve one-bedroom units and four studios, all configured to maximize occupancy and revenue potential. Located less than a mile from Asheville’s core attractions—including its nationally recognized dining scene, River Arts District, and cultural amenities—the property benefits from consistent year-round demand. With dedicated parking, an active and compliant STR license, and a structure that cannot be replicated under current regulations, this asset offers a rare combination of scale, location, and operational upside for an investor seeking to establish or expand a presence in one of the Southeast’s most resilient short-term rental markets.

42 Furman Avenue, Asheville
$479,000
2 Baths ⋅ 4379476 MLS
Free sign advertising to 28,000 vehicles daily with this spacious office/retail space! Commercial space available in this updated home turned office. 5 private offices, 2 open areas of cubes or conference room, etc. Garage available for leased storage Sign in place highly visible from Hwy 601 (Cannon Blvd) New roof, HVAC, kitchen. freshly renovated and ready to lease or lease with option to own.

2801 S Cannon Boulevard, Kannapolis
$450,000
336803 MLS
5,000 sq ft steel building (50’ x 100’) in North Greenville County. Concrete floor, one bay door, two HVAC units, and a large fan. Located just off Highway 101 with easy access to Highway 11. Approximately 23.5 miles to Greenville and 14.6 miles to Travelers Rest. Ideal for your business or manufacturing needs.

Landrum
$1,900,000
4379135 MLS
DOWNTOWN OPPORTUNITY – MOTIVATED SELLER! Positioned just outside the heart of downtown Monroe, this 5+ acre industrial property offers over 9,200 SF with unlimited potential for investors, developers, entrepreneurs, or owner-users seeking a high-visibility property with flexible zoning and multiple income-producing possibilities. Zoned General Industrial, the property is ideal for commercial parking, warehouse/distribution, contractor operations, automotive services, flex space, storage, manufacturing, or a mixed-use redevelopment concept. Over 50% of the site is already improved with gravel and concrete, allowing for easy access, equipment storage, fleet parking, or outdoor business operations. The main warehouse building features high ceilings and two loading docks (front and rear), providing excellent functionality for industrial or distribution use. Attached is an additional building well-suited for showroom, office, retail, or reception space. A detached accessory building offers even more flexibility — use it for additional workspace, storage, or immediate rental income. Investors may also explore leasing individual rear shop spaces to automotive or trade-related tenants for multiple streams of income. For buyers with a creative vision, this property presents a rare chance to create a unique downtown destination. The industrial character, proximity to the railroad tracks, expansive outdoor space, and location near the new police and fire stations make it an ideal setting for a brewery, distillery, food hall, entertainment venue, artisan marketplace, event space, or trendy mixed-use concept. The large outdoor areas could easily accommodate live music, games, food trucks, festivals, and community events. Several public parking areas nearby add to the accessibility and appeal. Additional features include industrial power, city water/sewer/gas, abundant front and rear parking, loading docks, accessory structures, and vacant possession for immediate redevelopment. The property does need renovation, but the possibilities here are truly endless. Bring your ideas, your plans, and your vision — and transform this property into the next destination or income-producing asset in one of Monroe’s growing downtown areas. Partial ownership opportunities may also be considered.

601 N Charlotte Avenue, Monroe
$400,000
4378852 MLS
Great location in the city of Locust close to Intersection of Hwy 24/27 and Meadow Creek Church Rd. Property has tenants in place please do not disturb. Property includes house and duplex which have tenants in place on verbal month to month lease. Value is based on acreage and future development potential. This property adjoins other listed parcels that have frontage on Main Highway. Development possibility to be confirmed with Locust Planning and Zoning by buyers agent. Property being sold as is, seller to make no repairs or improvements.

113 Meadow Creek Church Road, Locust
$685,000
336673 MLS
Redevelopment opportunity in the booming Hwy 290 area. The property consist of 2 parcels currently. One has the commercial building and the other has a 3 bedroom, 2 bath house. Great corner lot with approximately 190 feet of road frontage on Reidville Rd and approximately 220 feet on Smith Rd. Almost an acre total. The possibilities are endless on this one. Don't miss out on this great investment opportunity.

Moore
$450,000
1590504 MLS
5,000 sq ft steel building (50’ x 100’) in North Greenville County. Concrete floor, one bay door, two HVAC units, and a large fan. Located just off Highway 101 with easy access to Highway 11. Approximately 23.5 miles to Greenville and 14.6 miles to Travelers Rest. Ideal for your business or manufacturing needs.

993 Barton Road, Landrum
$4,200,000
4378133 MLS
Located in one of the last remaining undeveloped corridor in Matthews. Strategically located at the intersection of E John St and I-485 (Exit 52). Consult with Matthews planning and zoning department regarding uses. This is an assemblage of 4 different parcels totaling approximately 10.4 acres. Potential for a joint venture with the current owners. Please do not walk property without permission. Some houses still have tenants.

1828 E John Street, Matthews
$3,495,000
4370118 MLS
4 Medical Park Drive in Asheville, North Carolina represents a compelling investment opportunity within one of Western North Carolina’s most established and desirable medical parks. This well-maintained medical office building encompasses approximately 8,911 square feet of highly functional clinical and administrative space, situated on a 0.71-acre parcel. Purpose-built for medical and dental use, the property is thoughtfully configured with dedicated exam rooms and a surgical suite, allowing for immediate occupancy by a wide range of healthcare providers. Originally constructed in 2000 for an owner-occupant, the facility has been consistently operated as an oral surgery practice, underscoring its suitability for specialized clinical use. The site offers strong accessibility and parking capacity, featuring upper and lower parking areas with a total of 26 striped spaces, along with the potential to add additional parking if needed. Existing medical and dental infrastructure is in place, including a backup generator (currently not operational), providing a solid foundation for future upgrades or continued use. Overall, 4 Medical Park Drive delivers a rare combination of location, functionality, and adaptability—positioning it as an attractive option for both investors and owner-users seeking a presence in Asheville’s thriving healthcare market.

4 Medical Park Drive, Asheville
$1,500,000
4377752 MLS
Prime retail or mixed use development site located along US 74A just a short distance off I-40/I-240 (exit 53) & the Blue Ridge Parkway! This "gateway" link connects Fairview, Chimney Rock and Lake Lure with greater Asheville. Road frontage of ~139' along US 74A widens to ~278' a short distance into the site with more than 50% of the site zoned CS (~955' depth) while the remainder (wooded) site extends another ~615' (depth) increasing in elevation to a wooded plateau @ ~2410 elevation! Size & shape are conducive to split retail & residential use similar to other surrounding land uses along the corridor; sweeping, long range southern mountain view are a bonus! Utilities available!

Charlotte Highway, Fairview
$675,000
4377710 MLS
Discover an exceptional investment or owner use opportunity in the heart of downtown York, SC. Located at 107 S. Congress St. This 1,800 SF solid brick office building offers prime visibility and a classic exterior. The interior features a highly versatile layout, including a large, welcoming open lobby/reception area, multiple private offices, original bank vault, kitchenette and private restrooms. Perfect for professional services such as law firms, insurance agencies, real estate offices, or counseling services. This property boasts a desirable central location, providing easy access to local amenities and the York County Courthouse. Don't miss this opportunity to own a piece of historic York. Must close by end of August

107 Congress S Street, York
$1,100,000
4377311 MLS
LOCATION, LOCATION, LOCATION!! SELLER HAS CLEARED THE PROPERTY AND ADDED TWO CONCRETE APRON ENTRANCES FOR EASY ACCESS TO BOTH TRACTS. SELLER ALSO HAS ENGINEER PLANS APPROVED BY THE CITY FOR A CONVENIENCE STORE AND POTENTIAL RETAIL SHOP. AGAIN, PLANS ARE ALREADY APPROVED!! PLANS WILL CONVEY UPON CLOSE. THIS WOULD BE A GREAT LOCATION FOR A MEDICAL,OFFICE OR RETAIL COMPLEX. THERE IS A HIGH VOLUME OF TRAFFIC AND THE AREA IS GROWING FAST. CHARLOTTE PIPE RECENTLY RELOCATED TO THEIR NEW FACILITY LESS THAN 7 MILES AWAY. SELLER IS WILLING TO SELL THE TRACTS SEPARATELY. TRACT 1 @ 1.78 ACRES, WHICH WOULD BE 103 CHARLOTTE ST. IS $499,000, AND TRACT 2 @ 2.36 ACRES, WHICH WOULD BE 101 CHARLOTTE ST. IS $799,000.

101 Charlotte Street, Stanfield
$429,000
20300788 MLS
11.28 Acres that fronts both Hwy 11 and Rock Hill Road giving you access from both roads. This property has great potential for a business with easy access to I-85. Property lays well with a mixture of trees and has been underbrushed and well maintained with creek. This 11.28 Acres is placed in a growing area of Oconee County with good traffic count. Deed Restrictions may apply No Storage facility or Junk

11.28 Acres Hwy 11, Fair Play
$20,000
4376804 MLS
Opportunity to acquire a well-positioned parcel with excellent zoning in a highly convenient and rapidly growing area. This property offers strong potential for a variety of development uses, benefiting from its strategic location and continued growth in the surrounding market. Buyer is responsible for independently verifying all information, including zoning, water and sewer availability, utilities, and any applicable development requirements.

99999 Rocky Ridge Road, Asheville
$1,200,000
4375613 MLS
Exceptional opportunity to acquire a fully operational-ready event venue at 6815 Shiloh Unity Rd, Lancaster, SC. Situated on approximately 10.5 acres across two parcels, this 6,058± SF property offers a turnkey solution for an investor or owner-user seeking an established events facility in a growing market. The venue is already generating booking inquiries without formal marketing, reflecting strong organic demand and immediate revenue potential. The flexible layout and zoning support a variety of uses, including weddings, corporate events, and private gatherings, with a maximum occupancy of 250 guests. Expansive acreage allows for on-site parking, outdoor ceremonies, and future expansion, making this a rare opportunity with both current income and long-term growth potential.

6815 Shiloh Unity Road, Lancaster
$14,000,000
336529 MLS
Property is an improved commercial resort and conference center located on approx. 68 acres near Campobello, SC. Property is known as Old Mill Village built on a former wood mill site. Original office building was redeveloped into accommodations and event space beginning approx 2023, and additional conference space and accommodations buildings have been newly constructed on the property over the past three (3) years. Additionally, an outdoor amphitheater, sheltered event space, decks, and hiking trails have been newly constructed. There is ample room for further expansion and development of the resort and conference center for further venues and accommodations to be constructed near the dormant Norfolk Southern Railroad line that runs parallel to the property that is being converted into a bike and running trail from Sburg to NC.

Campobello
$675,000
4376137 MLS
Prime retail corner located at the crossroads of NC Hwy 9, Landrum Rd and Sandy Plains Rd in Tryon NC! This 4.44 ac. assembled site is one of the last development nodes in Polk County and connects both local & leisure traffic from SC to the Tryon International Equestrian Center and iconic Lake Lure! Located within the recreational triad of Lake Lure, Lake Bowen and the Tryon International Equestrian Center, this cleared, level, ready to develop "sleeper" site offers remarkable upside for a forward-thinking developer seeking to capitalize on the area’s continued growth and tourism-driven demand! Great for food service, retail or business services! Corner site with 195' frontage on NC Hwy 9 and 726' frontage along Landrum Rd! On-site waste treatment for any contemplated use is to be verified. Call agent today for details and a scheduled showing!

Nc 9 Highway, Tryon
$544,000
20300673 MLS
Excellent commercial parcel ideally positioned just off Clemson Boulevard, one of Anderson’s primary commercial corridors, and convenient to I-85 for easy regional access. This high-visibility corner is located adjacent to the Anderson Mall and surrounded by major national retailers, restaurants, and established businesses. The property offers outstanding potential for a gas station, retail strip center, or multi-use commercial development, with strong traffic counts and excellent exposure. Its strategic location provides consistent daily traffic and easy accessibility for both local and interstate consumers. Situated directly in the path of progress, this is a prime opportunity for investors and developers looking to capitalize on one of Anderson’s most active growth areas.

3101 Martin Luther King Jr. Boulevard, Anderson
$225,000
2 Baths ⋅ 1589826 MLS
2-unit income producing Central Business District property in downtown Lyman, SC with downstairs retail tenant already in place AND (54-A Groce Road) unfinished 1000+ sf residential living space with separate street-front entrance. Retail property features storefront showroom with great visibility and addition flex-space for office, storage, or retail expansion. Strong location with steady traffic and long-term growth potential in and emerging Lyman market. With an existing lease in place, strong street presence, and functional layout, this property presents a solid opportunity for investors seeking steady income with future upside in a growing Upstate market. Front door is within walking distance to Restaurants, Salons, Retail, and Grocery Stores.

54 Groce Road, Lyman
$155,000
4375035 MLS
Buildable lot with office zoning in West Asheville! Ready to build your commercial building, residential home, or multifamily. Per the Asheville UDO, "a mixture of office and residential uses is permitted in the Office District." Easy access to Haywood Road and Patton Avenue amenities - shops, restaurants, grocery stores, and more. This lot is mostly cleared with a few mature trees and a gentle slope. City water & MSD sewer are accessible per seller. Recent survey available.

Lot 108 Mace Avenue, Asheville
$450,000
20300584 MLS
5,000 sq ft steel building (50’ x 100’) in North Greenville County. Concrete floor, one bay door, two HVAC units, and a large fan. Located just off Highway 101 with easy access to Highway 11. Approximately 23.5 miles to Greenville and 14.6 miles to Travelers Rest. Ideal for your business or manufacturing needs.

993 Barton Road, Landrum
$5,000,000
4375691 MLS ⋅ Winston Townes BLDG.
Introducing The Winston Townes - a newly built 14-townhome investment opportunity in one of Statesville’s fastest growing locations, just 2 minutes from downtown. For savvy investors seeking substantial first-year tax advantages, this community offers a rare opportunity for potential bonus depreciation benefits estimated between $1,000,000 and $1,300,000 in year one (buyer to verify with there tax professional). Ideal for investors targeting: strong cash flow potential, new construction with lower maintenance, strategic growth market positioning and significant cost segregation / depreciation upside. Positioned in a prime location near downtown Statesville’s expanding retail, dining, and employment base, Winston Townes combines modern product with powerful tax strategy. Opportunities like this are rare. To be completed December 2026.

1013 Caldwell Street, Statesville
$225,000
336433 MLS
Income-producing property located in the Central Business District of downtown Lyman with an established retail tenant currently occupying the main-level retail space. The unfinished upper level offers excellent potential for residential living, office space, or a loft apartment and features its own separate street-front entrance and address. The retail portion features a street-facing showroom with outstanding visibility, along with additional flexible square footage suitable for storage, office use, or retail expansion. The existing lease provides immediate income potential while allowing future upside opportunities for the upper level. Positioned in a high-visibility location with steady traffic counts and strong long-term growth potential, this property is well-situated in the rapidly growing Lyman market. With strong street presence and a functional layout, this property presents an excellent opportunity for investors seeking steady income and long-term potential in the growing Upstate market. Conveniently located within walking distance to restaurants, salons, retail shopping, and grocery stores.

Lyman
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“ Based on information submitted to the MLS GRID as of . All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Some IDX listings have been excluded from this website. Properties may or may not be listed by the office/agent presenting the information © 2026 Canopy MLS as distributed by MLS GRID”

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