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Commercial Real Estate for Sale in Upstate SC

Commercial activity in the Upstate follows the interstates. I-85 between Greenville and Spartanburg carries the industrial and distribution demand, with BMW and its supplier network anchoring most of it; retail and office concentrate around the two downtowns and the Highway 9 and Fairview Road corridors.

Commercial runs on different diligence than residential — zoning and permitted use, environmental history, existing leases and their remaining terms, and what a building can actually be converted to. Tell us what you are trying to do and we will scope the search.

Commercial Listings

$1,150,000
4382296 MLS
Rarely available office condo opportunity located within an established 6-unit complex in one of Charlotte’s highly desirable business corridors, just minutes from the heavily traveled Independence Boulevard. This versatile two-level commercial space offers exceptional flexibility for investors or owner-users seeking a well-positioned property with strong long-term potential. Currently configured and operating as a day spa, the layout features multiple private rooms, several bathrooms, reception and waiting areas, and functional spaces designed to accommodate a variety of professional or medical-related uses. The existing setup allows for an easy transition for another spa, wellness, aesthetics, massage therapy, salon, chiropractic, counseling, or other healthcare-related business with only nominal upfit required. The flexible floor plan also makes it suitable for traditional office use, boutique professional services, or creative workspace concepts. The property benefits from excellent accessibility, convenient parking, and close proximity to major retail, dining, and residential areas throughout Charlotte. Its strategic location near Independence Boulevard provides strong visibility and quick access to Uptown Charlotte, Matthews, and surrounding submarkets, making it an attractive destination for both clients and employees. Whether you are searching for an investment property with income potential or a space to establish and grow your own business, this commercial condo presents a unique opportunity in a limited-supply market. The combination of location, functionality, and adaptability makes this a highly desirable asset for a wide range of professional uses. Opportunities like this rarely become available in this area. Don’t miss the chance to secure a flexible commercial property in one of Charlotte’s most convenient and rapidly growing corridors.

5808 Monroe Road, Charlotte

$299,900
20301334 MLS
Step into a piece of Walhalla’s history with this impressive 4,486 square foot brick commercial building located on Main Street in the heart of downtown. Constructed after the Great Walhalla Fire of 1898, this timeless property blends historic character with incredible redevelopment potential. Formerly home to the well-known Mountain Mocha retail space and coffee shop, the building features a spacious main level along with a full basement, offering ample square footage for a wide range of business opportunities. Original hardwood floors, classic architectural details, and a massive walk-in safe—featuring the historic Bauknight name etched above, a nod to the building’s origins as one of the town’s first general stores—add unmatched charm and authenticity. The layout allows for easy conversion into multiple units, with the potential to divide into up to three separate commercial spaces, each with its own entrance. Rear access from Catherine Street provides convenient entry to both the main level and basement, along with direct access to a city parking lot, making parking easy for customers and tenants alike. With its prime location, rich history, and flexible layout, this is a rare opportunity to own one of Walhalla’s most iconic buildings, offering endless possibilities for retail, dining, office space, or investment. The City of Walhalla currently provides several incentive opportunities, including a façade grant, signage grant, and the “Uniquely Walhalla” grant program — contact us for additional details. This is truly a must see.

109 Catherine Street, Walhalla

$1,275,000
20301154 MLS
Established commercial location just 3 miles from I-85 with lay down yard, 60x40 metal building, office space and incredible landscaping. 17270 SC Highway 11 is ideal for landscapers, construction companies, dock companies, builders, or any industry needing room to grow. Customers will enjoy all of the special spots on this property, like the stone firepit with waterfall, the pergola with fireplace, the astroturf zone and all with beautiful flowers, shrubs and trees surrounding the property. A brick paver driveway instantly elevates your customers' experience as they pull up to the office building. Inside is a reception area, handicapable bathroom, two offices and a covered back deck. Behind the office building is a 60x40 metal building featuring two roll up doors, one man door, heat and insulation. There is also a large lean-to attached to this building, perfect for covered storage of equipment or materials. The area around the metal building is fully fenced in with large double gates and barbed wire for extra security. Above this area is the lay down yard, which already has several bays for rock, mulch, sand and other materials. Or use this space to park equipment or vehicles. The property features approx 6.67 acres on a proposed plat, 619ft of frontage on SC Hwy 11 and approx 363 ft of frontage on Rock Hill Road, providing access from either side. The SC Visitors Center on I-85 is 3.2 miles from this location, making it one of the first businesses visitors from Atlanta and other destinations will see when they enter South Carolina. It is 2.1 miles from Lake Hartwell State Park and minutes to several lakefront neighborhoods. Companies servicing Lake Hartwell, Lake Keowee, Clemson, Seneca, Anderson, Lavonia, Toccoa, Hartwell and other areas will find themselves centrally located. SHOWN BY APPOINTMENT ONLY, please do not disturb the business.

17270 SC 11 Highway, Fair Play

$3,550,000
4379843 MLS
This versatile industrial/commercial opportunity offers over 30,000 SF of brick construction situated on 8.67 acres in rapidly growing Lancaster County. The expansive building features multiple separated sections ideal for office space, warehouse operations, storage, showrooms, manufacturing, distribution, or flexible multi-tenant use. Multiple loading docks service the main building, providing excellent accessibility for shipping and receiving operations. Heated and cooled office areas offer comfortable workspace, while the remaining portions of the building provide substantial open industrial space ready for customization. A front parking lot accommodates customers and employees, with additional land behind the building offering potential for expanded parking, storage, or future development. A detached storage building further enhances the property's functionality and flexibility. This offering becomes even more attractive with 2 adjacent parcels available for purchase or lease. The adjoining parcel (LOT B) consists of approximately 12 acres of partially cleared raw land with existing driveways installed. All parcels have been county-approved for use as a concrete plant, creating exceptional potential for industrial users, contractors, manufacturing, or expansion operations. LOT C is a 6 acre parcel with multiple concrete pads. Located in Lancaster County, an area known for aggressive industrial incentives and continued growth, this property presents a rare opportunity for investors, owner-users, or expanding businesses seeking flexibility, acreage, and future development potential. Please note full details for the sale or lease of all 3 lots are as follows: LOT A sale MLS #4379843 Lot A lease MLS #4379966 LOT B sale MLS #4380263 LOT B lease MLS #4380266 LOT C sale MLS #4402847 LOT C lease MLS #4402866

2881 Landsford Road Unit #A, Lancaster

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