Commercial Real Estate for Sale in Upstate SC

Commercial activity in the Upstate follows the interstates. I-85 between Greenville and Spartanburg carries the industrial and distribution demand, with BMW and its supplier network anchoring most of it; retail and office concentrate around the two downtowns and the Highway 9 and Fairview Road corridors.

Commercial runs on different diligence than residential — zoning and permitted use, environmental history, existing leases and their remaining terms, and what a building can actually be converted to. Tell us what you are trying to do and we will scope the search.

Commercial Listings

$175,000

2 Baths ⋅ 1569677 MLS

A Commercial restaurant/convenient store opportunity with newer equipment! This 1500 square feet building currently set up for a takeout restaurant and convenient store. The restaurant has a commercial grill and commercial pizza oven. The building also offers a separate living area attached to the store for the owner to live in while operating the business. The possibilities are endless on this property new owner could remodel and add sit down restaurant or expand the convenient store. The separate living area has separate entry and offers 1 bedroom, kitchen, 1 bath and laundry room. Call today to schedule a private tour.

701 Union Highway, Cross Anchor

Cross

Development Opportunity in South Asheville. 51.65/ac tract now available. Paved road to the Property. Curb & Gutters are in place with access to public water and sewer. Woodland Meadows has access to traffic light on Sweeten Creek Road, next to and behind the New Ellison apartments. This property was approved for 11 Single Family lots per Buncombe County Board of Adjustments. PUD was approved. The properties are on both sides of Woodland Meadows Rd. Could be sold in 2 tracts (Tract A 27.84/ac and Tract B 23.81/ac). Great Mountain views. Two Tax PINS: 9656-31-9340 & 9656-42-3541. Property runs up the hill to cul-d-sac. Property Zoned R-LD.

105 Woodland Meadows Drive Unit #Tract A & B, Asheville

$799,900

4302190 MLS

Great commercial location 19 approximate acres. High traveled area. South York Hwy is a main road between Gastonia, North Carolina & South Carolina. Includes 2 parcels PID #306241 & PID #114854. Zoned commercial RS-12 & C-3 as per city of Gastonia. City water & sewer available in area.

00 York Highway, Gastonia

$799,000

20292553 MLS

BEST LOCATION IN DOWN TOWN SENECA ! Prime Downtown Seneca Commercial Opportunity – 124 & 118 N Townsville St OPPORTUNITY ZONE ! This exceptional dual-property, two store-fronts commercial building in the heart of downtown Seneca, SC offers high visibility 11,500 VPD and unparalleled foot traffic. The Ye Old Sandwich Shoppe Restaurant (124 N Townsville) has 3224 SF and the Ice Cream/Confections Shoppe with large banquet room for celebrations (118 N Townsville) has 2548 SF. Both spaces present a unique opportunity for an established business or investor. These buildings feature 5772 SF, Hydro-Top Roof, Solar Hot Water With Electric Backup, Three HVAC'S. Situated in a vibrant downtown location, this property is perfectly positioned to capitalize on the city’s exciting developments: the new 702-Seat Performance Arts Center being constructed a few feet away directly beside the buildings estimated opening December 2026 and a 2000 seat State-Of-The-Art amphitheater just one block away opened June 19th, 2026. These upcoming venues are expected to draw significant traffic, making this location a prime hotspot for dining, retail, and entertainment businesses. Enjoy the Jazz Fest with live entertainment every Thursday evening during the Spring, Summer, Fall featuring a block party with street dancing and out door dining ! Don’t miss your chance to own a highly visible, strategically located property in a growing downtown area with strong economic and cultural activity. Buildings can be offered separately. Ye Ole Sandwich Shoppe Restaurant 3224 SF at 124 N. Townville Street and the Ice Cream Store 2548 SF at 118 N. Townville Street. Owner financing terms available. Owner retired, both buildings are vacant.

124 and 118 N Townville Street Unit Ye Ole Restaurant, Seneca

$499,000

5 Baths ⋅ 4301955 MLS

Attention investors! Restaurant with Endless Potential! Currently renovated upstairs, with more renovations to come downstairs to use for apartment spaces. This commercial property offers over 7,600+ sq. ft. of space and comes turnkey ready as a restaurant—complete with all equipment! On the main floor, you have 4,332 sq. ft. currently designed for restaurant operations featuring a functional layout and updated finishes. In the partially finished basement, you have 3,292 sq ft of space with two bathrooms and flexible rooms ideal for offices, storage, or additional income-producing space. The unfinished portion of the basement provides ample storage solutions, while the partially finished flex rooms offer the perfect setup for leased office space or expansion. The building has been completely renovated within the last year, giving buyers peace of mind and a professional, move-in-ready space. Outside, a large parking lot with ample parking and handicap-accessible spaces ensures customer convenience. Currently operating as a restaurant, the property’s versatile layout makes it an excellent fit for a variety of uses—such as a convenience store, gas station, freestanding retail, or other commercial ventures. This is a rare opportunity to purchase a fully equipped, renovated commercial property with multiple streams of potential income. Call today!

4768 Us 221a Highway, Mooresboro

$949,000

7 Baths ⋅ 4301646 MLS

HISTORIC CHARMER SEEKS LOVING NEW OWNER. Beautiful, 7-unit building in Kenilworth on a flat lot with loads of architectural personality. Have you been looking for a cool investment property in a prime location? This is the one! Centrally located near schools, hospitals, downtown Asheville, and Biltmore Village. Complete with a coin laundry, common spaces, and off-street parking. It's an elegant and distinguished building with solid 'bones' that's ready for its next chapter in ownership!

15 Grindstaff Drive, Asheville

$350,000

328692 MLS

3-33-00-063.01 & 3-33-00-063.02 land property has 10+- ac with a 6000+sqft brick building. it has large parking lot with an entrance and exit. The property is located very conveniently to hwy 176 (Furman Fendley hwy). the property is short drive from downtown Spartanburg , Union or even Gaffney . it is very convenient to the new hospital in Union. great location for housing or business . Very nice area with a lot of potential. AS IS.

Pacolet

$3,290,000

4300210 MLS

Exceptional commercial development opportunity on Merrimon Avenue (US 25) featuring an assemblage totaling 1.66 acres with approximately 300 feet of road frontage. Lots are Zoned CBI and RS8, offering a versatile mix of commercial, residential and mixed-use development potential. The site includes five existing buildings with short term leases, providing immediate rental income. Positioned in the heart of a high-traffic, primary commuter corridor, and surrounded by national retailers including Trader Joe’s, Whole Foods, and Harris Teeter, this site ensures excellent visibility and strong consumer appeal. Signalized access to Merrimon Avenue via a 35+/- foot wide curb cut on Hillside Street, and multiple curb cuts on Merrimon Avenue provide ease of ingress/egress. Strategically located less than 1 mile from Downtown Asheville, I-240 and I-26, and just 3 miles from I-40, the property offers seamless connectivity across Asheville and beyond. This rare opportunity presents investors and developers with a phenomenal chance to activate an underdeveloped site on one of Asheville’s most sought-after thoroughfares.

210, 212 & 230 Merrimon Avenue, Asheville

$850,000

4301197 MLS

Prime commercial opportunity in the heart of Hickory! This versatile property offers excellent visibility and accessibility, making it ideal for a wide range of business uses. Previously utilized as a school, the building provides a functional layout with multiple rooms, open areas, and flexible space that can be adapted for offices, educational use, medical, retail, or specialty business operations. Situated on a sizable lot with convenient access to major roads, the property offers ample parking and room for future improvements. Investors and owner-users alike will appreciate the potential for strong returns in this growing market. Whether you are expanding your portfolio or seeking a location for your business, this property is a rare find in an established Hickory corridor.

925 Ne 5th Ne Street Unit #15, Hickory

$170,000

4300501 MLS

Fantastic opportunity to own a great corner lot with high visibility along Highway 70. This property is zoned for manufacturing, making it ideal for a wide range of business ventures. Conveniently located with easy access to Interstate 40, it ensures excellent connectivity for transportation and distribution. Don’t miss this chance to secure a property with both visibility and versatility!

2748 Us 70 E Highway, Valdese

$700,000

4300739 MLS

Incredible land opportunity. Situated at a corner lot with an impressive 302ft of frontage on Waxhaw Indian Trail Rd, this parcel offers numerous possibilities. Zoned for multiple uses including storage, retail, office, and daycare, it's an ideal investment for developers or those seeking prime real estate. Don't let this chance slip away to secure a strategic location with high visibility and potential.

1111 Waxhaw Indian Trail Road, Indian Trail

$4,200,000

4300142 MLS

2 Parcels equaling 17.62 Acres. 349 ft HWY 150 frontage.

8042 Nc Highway 150 E Highway, Terrell

$1,349,990

20291560 MLS

Great commercial building on Hwy 123 in Clemson. Building is 6000 square feet with ample parking and a traffic count of 30K per day.

990 Tiger Boulevard, Clemson

$850,000

20292192 MLS

19.70-acre property with a combination of land, multi-family housing, and a commercial building. The property has 4 single-wide mobiles that are currently rented and great condition. The 1000 sqft shop with 2 bay doors and an office. The land behind the improvements is heavily wooded with large hardwoods and has a creek. Great income. close to Anderson and I-85. Public water is available. No county zoning. Incredible condition. Estimated cap rate of 7+% and plenty of opportunities for growth and expansion. Shown by appointment only.

1425 Amity Road, Anderson

$3,000,000

4299381 MLS

418 N Oakland Street, Gastonia

$500,000

4298289 MLS

Rare opportunity for commercial property located directly on Highway 74 in Wingate. This property offers a unique opportunity for entrepreneurs, developers or investors seeking a high traffic location along with long-term growth potential. Situated just steps from Wingate University and surrounded by a growing mix of local businesses and student housing, this property is ideal for retail, dining, service businesses or offices. Easy access from either Highway 74 or S. Main Street and walking distance to campus, downtown and residential neighborhoods.

Hwy 74 Highway, Wingate

$1,700,000

4297513 MLS

Available lots in the Cross Creek Medical/Office Park which is situated between Highway 74 and Highway 601 in Monroe with primary access to Highway 74, a major commercial highway in an area referred to as Hilltop. This is a high traffic area providing a great location for medical and office development opportunities along with being conveniently located near Atrium Health Union hospital, restaurants and businesses.

Charles Hunley Lane Unit #4-13, Monroe

$1,900,000

328297 MLS

Location, location, location! Exciting development opportunity in the heart of Woodruff, an up-and-coming area just 20 minutes from Greenville and Spartanburg. Award-winning District 4 Schools, including the new Woodruff High School, are within a mile. Nearby industries include the BMW Battery Plant. This 30-acre parcel is ready for development, currently zoned in the county. Water is available, and sewer is in neighborhood next door. The property includes two tax map IDs: 4-41-00-026.00 and 4-41-00-026.05, with a power line easement.

Woodruff

$595,000

4297538 MLS

b u y M A I N S T, THIS MAY BE THE "LAST TIME" TO BUY AN OPEN CORNER ON US HWYS IN HISTORIC DOWNTOWN HENDERSONVILLE, NAMELY "MAIN STREET" AND "KING STREET" ... A HOMETOWN CARLOT FOR DECADES. CAN NOW BE ""YOUR"" HENDO LANDMARK, WHAT COULD YOU DO HERE, CALL ME! YES, THIS WORLD IS CHANGING IN HENDERSONVILLE, 100-15O YEARS AGO WE WERE RIDING HORSES, WAGONS, ETC. THEN ON OUR MAIN STREET FORDS AND CHEVYS AND EVEN DUSENBURGS, AUBURNS, TODAY ANYTHING INCLUDING ROLLS ROYCE AND KIAS ... PRE-DOMINATE THING NOW HERE IS ""ROUND-ABOUTS" ... DRIVEBY AND NOTICE FROM THIS POINT/CORNER ... LOOK SOUTH ... MOST IS GONE, ... LOOK NORTHWARD AND SEE DOT PLANS/RUMORS, WHERE THE HVL "WELCOME TO" SIGN IS TO BE LEVELLED/GONE ... PLANS FOR SURE CAN BE CHANGED ... BUT KEEP IN MIND THIS PROPERTY FOR SALE DOES HAVE NEW RIGHT OF WAY POINTS, BUT IT WILL BE THERE ... AND VALUABLE- WHOMEVER'S IT IS THERE. COULD BE YOU. MOST ALL OF US LOVE THIS BEAUTIFUL LITTLE MOUNTAIN TOWN ... TAKE A TRIP TO CHARLOTTE, ATLANTA, EVEN ASHEVILLE ... NONE HAS THE SAME AS HISTORIC DOWNTOWN AS HENDERSONVILLE. MY FAMILY AND I EARLIER TODAY VISITED THE APPLE FESTIVAL, ATE THE BEST PIZZA AT MEZZALUNA'S , THEN THE BAKERY SHOP, BOUGHT A BOX OF APPLES AND ALL DRANK SOME CRUSED ICE CIDER, MEMORIABLE SIMPLE FUN, NOW WAS IT THE FOOD OR THE MOMENT, NO CARS, NO GUNSHOTS, NO FIGHTS. YOUR BUSINESS CAN BE HERE, WITH OWNER FINANCING. CALL ME, MOVE ON IT SOON, NOT LATER.

421 S King Street Unit #3627, Hendersonville

$2,290,000

4296404 MLS

Opportunity for almost 6 acres in the heart of Troutman. Surrounded on three sides by Iredell County owned property that includes the Iredell County Rec Center and the Iredell County Fairgrounds. Turning into the facility off of Main St, you will cross over the active rail road and the newly installed Greenway Walk for the rapidly growing Town of Troutman. The growth and expansion of Troutman is at an all time high with no signs of slowing. This facility could possibly be rezoned if need be to accommodate lots of uses. Ceiling heights vary through out from 9' to almost 12'. Facility is sprinklered.

694 N Main Street, Troutman

$3,499,000

11 Baths ⋅ 1567803 MLS

Rare opportunity in the fastest growing part of downtown Greenville to buy 3 and 1/2 buildings with current cash flow. Excellent parking with 10 spaces per building and 1/2 ownership in the back overflow parking lot. Road signage available for each unit. Currently occupied is 75% of space available, located 3 blocks from the University Square redevelopment and 1 block from South Main Street. Call today for more information. Agent is owner

413 Vardry Street, Greenville

$470,000

4231360 MLS

Commercial/Investor Interest? This well-maintained mobile home park offers a convenient location near the South Carolina border, minutes from the Tryon International Equestrian Center, and a day's drive to Asheville and back. The sale includes 2.1 acres with six homes conveying, plus one leasehold home owned by the occupant (does not convey), with 4 tenants currently in place. There are three additional lots (septic, county water, and electric needed) to create the potential for a total of 10 income-producing sites. Features include an established rental history, septic systems, county water, and electric. Recorded easement for access to the rear property and two titles to be signed at closing. This is turn-key with even more potential! No HOA fees or additional dues.

1803 Hines Road, Mooresboro

$450

1567463 MLS

Professional office space For Lease at 300 John St, Greer, SC 29651, unit 6B Space 1, $450/Month. 2nd Floor Individual Office, 130 SF 11.5x11.5 Office, shared large 21.5x21.5 cubicle / conference room. Tenant pays rent only. Owner pays property tax, CAM Fee and Utilities. Space 2, $1400/Month. The entire 1st floor, it has about 1000+/-SF. 4 individual offices, 2 ADA bathrooms and storage space. Tenant pays rent only. Owner pays property tax, CAM Fee, and Utilities. Conveniently located off Wade Hampton Blvd. Close Proximity to GSP Airport, easy access to Hwy 101, 14, I-85 & I26 Zoning: C2 City of Greer.

300 John Street Unit 6B, 2nd Floor Individual Office, Greer

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The Listings data contained on this website comes from various participants of The Multiple Listing Service of Greenville, SC, Inc. Internet Data Exchange. IDX information is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The properties displayed may not be all the properties available. All information provided is deemed reliable but is not guaranteed. © 2026 Greater Greenville Association of REALTORS®. All Rights Reserved. Last Updated

“ Based on information submitted to the MLS GRID as of . All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Some IDX listings have been excluded from this website. Properties may or may not be listed by the office/agent presenting the information © 2026 Canopy MLS as distributed by MLS GRID”

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