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Commercial Real Estate for Sale in Upstate SC

Commercial activity in the Upstate follows the interstates. I-85 between Greenville and Spartanburg carries the industrial and distribution demand, with BMW and its supplier network anchoring most of it; retail and office concentrate around the two downtowns and the Highway 9 and Fairview Road corridors.

Commercial runs on different diligence than residential — zoning and permitted use, environmental history, existing leases and their remaining terms, and what a building can actually be converted to. Tell us what you are trying to do and we will scope the search.

Commercial Listings

$1,500,000
2 Baths 1579545 MLS
BACK ON THE MARKET!!! through no fault of seller...12+ remarkable acres and a 2600 sq ft multipurpose building that could be used for various business opportunities. With a LONG QUIET DRIVE across an existing CREEK, to the ELEVATION of parcel#2, PRIVACY AND SECLUSION meet HIGH VISABILITY depending on needs and development. This could be the perfect place for another WORSHIP CENTER, WELLNESS FACILITY, OR RETREAT CENTER while offering a sanctuary as well for woodland creatures with it's creek, small pond area, fruit trees, etc. DEVELOPERS AND INVESTORS could take advantage of these parcels to create roomy estate style homes, multi family units, RV or tiny home communities... endless possibilities. With TWO RESTROOMS and four additional rooms at each corner, along with the LARGE, OPEN AUDITORIUM with HIGH CEILINGS, this property opens itself up to almost anything your mind can imagine. Located just off HIGHWAY 26 AND HIGHWAY 123 INTERSECTION and minutes from HWY 81 AND I-85, DOWNTOWN GREENVILLE AND EASLEY you get the CONVENIENCE of city life and ease of travel, as well as the QUIET OF RURAL LIFE. New Easley Highway and Highway 25 both have PROGRESSIVE TRAFFIC COUNTS ensuring HIGH VISIBILITY if you choose to develop and the acreage to expand exponentially. Surrounded by various types of businesses and homes, with RM-20 zoning and a commercial variance (for the designated church, will need to be reapplied for by the new owner), your dreams are sure to fit this property. Greenville and Easley are constantly expanding as can be seen by the influx of new development along New Easley Hwy, 124 and 153, making the purchase of these parcels a SMART AND TIMELY INVESTMENT. All numerical representations including lot size, square footage, age, and room measurements-are approximations only and may be inaccurate. If Buyer's decision to purchase is based on numerical representations Buyer shall be responsible for verifying all information.

2415 New Easley Highway, Greenville

$399,000
1 Baths 4335254 MLS
PRICE ADJUSTMENT AND POSSIBLE OWNER FINANCING! NOW is the time to grab this AMAZING opportunity!! This freestanding commercial building offers a rare blend of classic character and functional flexibility in a highly visible and evolving location. Currently configured for office use, the interior is divided into multiple spaces that allow for private work areas and additional storage. Walls may be removed to create an open-concept layout, offering adaptability to suit a variety of business needs. The building features one bathroom, with plumbing already in place for a second, and has seen thoughtful upfitting throughout, including the addition and replacement of windows that enhance natural light while preserving its nostalgic charm. A distinctive staircase leads to an unfinished basement level, presenting endless possibilities for expansion, storage, or future build-out. Land conveys with the property, providing potential for expansion or further development. Convenient parking is available directly in front of the building, with close proximity to a nearby crosswalk allowing for easy access and supplemental parking options. Ideally located across from the proposed Saluda Rail Trail and the Nina Simone Plaza, this property benefits from strong visibility, walkability, and long-term growth potential. A classic structure with modern versatility, it is well-positioned for continued office use or creative commercial adaptation. CURRENTLY AN ACTIVE PROFESSIONAL BUSINESS SO CAN ONLY BE SHOWN BY APPOINTMENT.

55 S Trade Street, Tryon

$7,499,000
4333685 MLS
Price Improvement! Premier Lake Hickory Development Site with Established Campus Infrastructure – 23+ Acres, 3/4 mile of Lake Hickory shoreline. This exceptionally rare 23-acre waterfront offering on Lake Hickory in Conover, NC combines development-ready scale with a proven operational footprint. Zoned PD, the property is currently utilized as a fully functioning Boys Academy campus, demonstrating the site’s capacity, infrastructure, and regulatory viability for large-scale residential, institutional, or hospitality uses. The existing campus includes 12 buildings, featuring 35 bedrooms and 28 bathrooms, and is designed to accommodate approximately 65 overnight residents and up to 140 daytime occupants. Supporting facilities include a central dining hall, residential and administrative structures, a publicly operating zipline with dedicated facilities, a floating dock, a beach area, and a graveled 3/4+ mile walking trail around lake, all of which underscore the property’s adaptability and immediate functional value. From a developer’s perspective, this property offers a rare combination of: Approximately 3/4 mile of Lake Hickory shoreline, suitable for possible future premium waterfront homesites Contiguous 23+ acres with established internal circulation and utilities Existing vertical improvements, allowing for adaptive reuse, income generation, or phased redevelopment Proven operational history as both an academy campus and a short-term rental / Airbnb property Catwaba County Planning staff could support this property being rezoned as Residential R-40. Currently, PD zoned, supporting luxury residential and estate-style waterfront development The current Boys Academy use provides clear evidence of density tolerance, utility capacity, and access, significantly reducing unknowns for future redevelopment or repositioning. The site is well-suited for luxury lakefront estates, a private residential enclave, destination retreat, wellness or education-based reuse, or continuation of institutional operations. Strategically located near Hickory, Mooresville, and the greater Charlotte region, this offering represents a high-barrier-to-entry waterfront asset with both near-term income potential and long-term development upside. Large-scale Lake Hickory opportunities with this level of shoreline, zoning, and infrastructure are exceedingly rare. Note: listing residential MLS # 4334418

6692 Valwood Road, Conover

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“ Based on information submitted to the MLS GRID as of . All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Some IDX listings have been excluded from this website. Properties may or may not be listed by the office/agent presenting the information © 2026 Canopy MLS as distributed by MLS GRID”

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