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Commercial Real Estate for Sale in Upstate SC

Commercial activity in the Upstate follows the interstates. I-85 between Greenville and Spartanburg carries the industrial and distribution demand, with BMW and its supplier network anchoring most of it; retail and office concentrate around the two downtowns and the Highway 9 and Fairview Road corridors.

Commercial runs on different diligence than residential — zoning and permitted use, environmental history, existing leases and their remaining terms, and what a building can actually be converted to. Tell us what you are trying to do and we will scope the search.

Commercial Listings

$1,500,000
1 Baths ⋅ 4155745 MLS
Prime acreage with over 450' feet of road frontage located on a main thoroughfare , (U.S. Hwy 21N.) in Statesville's largest expanding retail area. Subject property is zoned H-B and suitable for large retail shopping, grocery, restaurant, entertainment and more. Utilities available, adequate topography, and drainage. All improvements and personal property are being sold as-is with no value. Subject property is strategically located on Hwy. 21 N. (Turnersburg Hwy.) in the rapid growth pattern between I-77/1-40 Interchange, approximately 1 mile south of I-77 at exit #54, and approximately 2 miles north of I-40 at exit #151. D.O.T. will allow two 50' curb cuts for this property.

555-565 Turnersburg Highway, Statesville
$2,995,000
4153008 MLS
The Red Rocker Inn & Restaurant is a charming Victorian-style inn built in 1896. Known for its distinctive red rocking chairs and front porch, the inn offers 17 comfortable guest rooms featuring antique furnishings and modern amenities. The warm, welcoming atmosphere is enhanced by the innkeepers' exceptional hospitality, ensuring guests feel at home. Located in the heart of Black Mountain, the inn is an ideal base for exploring the town's shops, galleries, and nearby Blue Ridge Mountains. Special events and customizable packages make it perfect for romantic getaways, family vacations, and group retreats, offering a blend of history, comfort, and culinary delight.

136 N Dougherty Street, Black Mountain
$425,000
1530041 MLS
5,000+- sqft commercial/flex warehouse space situated on a 0.57+-acre corner lot in Duncan, SC, 2+- miles to BMW Manufacturing with easy access to I-85. This facility is zoned Light Industrial in the Town of Duncan and equipped with a 400A 3-phase electrical service, one drive-in door, one dock-high door, and all utilities. Well suited for a wide range commercial purposes and a great opportunity for owner user or investor. Currently leased with immediate cashflow potential.

200 Woods Chapel Road, Duncan
$1,250,000
4151845 MLS
Zoned GB General Business Just South of Ballantyne South Charlotte Near Hwy 521 intersection Across from Lowes Indian Land, fastest growing area in S C Day Time Population 5 Miles 90,927 Average Household income 5 Miles $115,628 Tenant in older house on the property. Needs 45 days notice to vacate the house. House being sold at no value, no disclosure, as is.

224 Fort Mill Highway, Fort Mill
$1,700,000
4149807 MLS
Prime location NMX/RMX zone property below Windstone Apartments and directly across from Grainger Village. Perfect for office/commercial development. Listing consists of three parcels (2.91 Acres contiguous parcels North of Laurel Heights Drive and 1.62 Acres South of Laurel Heights Drive).

0000 Charlotte Highway, Mooresville
$595,000
20275740 MLS
Looking for place for your new business, to relocate your business or invest, then this one is worth a look! Now tenant occupied. Located in a prime location in Anderson County, this 5,000 square feet commercial building on two acres is only 10 miles to I-85 North and 7 miles to I 85 South. 2,300 Square feet of finished office space with a lobby, full kitchen with appliances, conference room, four offices and two restrooms is ready to go. 2,700 heated square feet of warehouse/shop space with three bay doors and full restroom will meet your need for work or storage. There is plenty of paved parking in front for customers and a fenced yard area for storage, an opportunity to add more buildings or maybe a residence. There are so many possibilities for this space, so come take a look today and make plans for your future!

3361 N 29 Highway, Belton
$595,000
3 Baths ⋅ 1528609 MLS
Looking for place to invest, then this one is worth a look! Currently tenant occupied. Located in a prime location in Anderson County, this 5,000 square feet commercial building on two acres is only 10 miles to I-85 North and 7 miles to I 85 South. 2,300 Square feet of finished office space with a lobby, full kitchen with appliances, conference room, four offices and two restrooms is ready to go. 2,700 heated square feet of warehouse/shop space with three bay doors and full restroom will meet your need for work or storage. There is plenty of paved parking in front for customers and a fenced yard area for storage, an opportunity to add more buildings or maybe a residence. There are so many possibilities for this space, so come take a look today and make plans for your future!

3361 Highway 29 N, Belton
$1,500,000
4136618 MLS
Prime 18 acre parcel on State maintained Murdock Road in Troutman with over 360 feet of road frontage. Builders, Developers and Investors will be interested in this growing area, close to Interstate 77 off exit 45. Troutman Land Use Master Plan shows 3 designations city will consider for development here; Highway Business, Light Industrial, and Heavy Industrial. This parcel has been rezoned to Light Industrial. Adjacent to the CATS Center (Career and Technical buildings) belonging to Iredell Statesville Schools South Iredell High School. Down the road from a large WalMart Distribution Center, and across from a Concrete Plant. Convenient to grocery, restaurants, and other businesses, and close to the Iredell County Fairgrounds where improvements will include a new agriculture center and farmers market soon to be under construction. Contact listing agent for attachments and Troutman master plan if needed. Also Listed Under Land MLS: 4126435

000 Murdock Road, Troutman
$3,000,000
4142464 MLS
Undeveloped acreage only! High traffic and high visibility area! Great hotel, retail, apartment, or gas station development potential! Approximately 500' of frontage on Steele Creek Road with utilities nearby. Less than 1/2 mile from I-485 and 1/10 of a mile to Shopton Road. Close to retail centers, Charlotte Premium Outlets, and Shopton Square. Good topography!

8151 Steele Creek Road, Charlotte
$49,000
4137910 MLS
PROPERTY HAS DETENTION POND AND STORM DRAINAGE EASEMENT ANY USE WOULD REQUIRE BUYER TO GET CITY APPROVAL . SERVEY ATTACHED.

1821 Dale Earnhardt Boulevard, Kannapolis
$245,000
20235716 MLS
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot9 N 29 Highway, Anderson
$585,000
20272821 MLS
Desirable high traffic property located right at I-85 and US 76-28 (Exit 19A) intersection. All Utilities are available. Great location for restaurant, corporate office, shopping plaza, wedding venue and many other business locations. More than 80,000 combined vehicles pass here each day on I-85 and Hwy 76 (Clemson Blvd) Exit 19B heading north 15 miles takes you to Clemson University, Anderson serves 6 Georgia counties for food, entertainment and shopping and is growing at a healthy rate! Nearby properties include beautiful Lake Hartwell, boat ramps, shopping centers, hotels, fast food and dine in restaurants, residential home and condos. Other large employers include Michelin, Arthrex, Ryobi, Electrolux, First Quality, Walgreens Distribution and many others. LOTS R-1-A AND R-1-B + R 2 (BEING SOLD TOGETHER) CAN BE PURCHASED TOGETHER FOR A TOTAL OF 6.06 ACRES ALL FOR ASKING PRICE OF $1,499,800.

Lot R-1-A Destination Boulevard, Anderson
$245,000
20235709 MLS
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot4 N 29 Highway, Anderson
$999,949
20242166 MLS
15,600 SF+/- historical 3 level brick free standing corner building one block from Ram Cat Alley. The owner's Young Fashions retail currently occupies the main level. Buyers to verify everything of importance including square footage. Opportunity Zone. Advance notice required to show !

235 Main Street, Seneca
$699,000
20268748 MLS
Great commercial tract(s) near Publix, Ingles, DG and more! This property sits just outside the city limits of Seneca near the intersection of Hwy. 123 and SC 130, and near Old Clemson Hwy. This unrestricted property consists of 2 adjoining tracts, offered together for one price, equaling 1.8 acres. Combined frontage on SC 130 is approximately 194 ft with a depth of just over 400 feet. Daily traffic count for this property is 9100. This is an excellent location for many types of business. Please confirm through due diligence that property is suitable for your needs.

1.8 Acres Rochester Highway, Seneca
$245,000
20235710 MLS
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot5 N 29 Highway, Anderson
$1,610,000
20208940 MLS

00 Blue Ridge Boulevard, Walhalla
$245,000
20235717 MLS
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot10 N 29 Highway, Anderson
$245,000
20235715 MLS
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot8 N 29 Highway, Anderson
$245,000
20235708 MLS
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot3 N 29 Highway, Anderson
$949,000
20272816 MLS
249' along I-85! Desirable high traffic property located right at I-85 and US 76-28 (Exit 19A) intersection. All utilities and storm drainage work complete with public road ready to access your business. Utilities available at property are water, sewer, electric and gas. Easy to access the interstate. Great location for restaurant, corporate office, shopping plaza, wedding venue and many other business ventures! More than 80,000 combined vehicles pass here each day on I-85 and Hwy 76 (Clemson Blvd) Exit 19B heading north 11 miles takes you to Clemson University and 6.5 Miles heading southwest on Hwy 76/Clemson Blvd. takes you to Anderson University. Anderson serves 6 Georgia counties for food, entertainment and shopping and is growing at a healthy rate! Nearby properties include beautiful Lake Hartwell, Portman Marina, boat ramps, shopping centers, hotels, fast food and dine in restaurants, residential homes and condos. Other large employers include Michelin, Arthrex, Ryobi, Electrolux, First Quality, Walgreens Distribution and many others. On Destination Blvd: Hilton Garden Inn, Fuddruckers, AJ's Bar and Grill - Within a mile of Panera's, Texas Roadhouse, Olive Garden, Longhorn, Hardees, Bojangles, Chick Fil-A, Chilis, and more! On the other side of Interstate: Waffle House, Wendy's, McDonalds, Arbys, Holiday Inn Express, Subway, Outback, Hooters, Wild Wings, Fairfield Inn, Country Inn & Suites, Comfort Inn & Suites, Starlight Movie Theater, Hampton Inn, and Cracker Barrel.

105 Destination Boulevard, Anderson
$156,500
20274011 MLS
Former lawyers office and stenographer office. Located in the heart of downtown Anderson, this 2,500 sq. ft. heated commercial space offers an exceptional opportunity in a rapidly growing area. Features include a brand-new city-installed parking lot and lighting with rear access. Ideal for a law office, retail shop, restaurant, or virtually any business venture you can envision. Within walking distance to local retail shops, restaurants, the courthouse, and the farmers market—plus just steps away from a new 167-unit apartment development with commercial parcels along the front. Downtown Anderson is expanding rapidly, and it’s becoming harder to find commercial land at this price point. Don’t miss your chance to secure a prime location in this vibrant community. Owner financing is available.

109 W Calhoun Street, Anderson
$245,000
20235711 MLS
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot6 N 29 Highway, Anderson
$3,833,000
20269332 MLS
76.66 acres with in the city limits of Seneca with all utilities available. The 31.66 acres that fronts the Frontage Road and Blue Ridge Blvd is Tax Map Number 520-80-01-002. Tax Map Number 520-80-01-001 45+/- acres is being surveyed for exact acreage located off of Knollwood Drive. New owner can apply for zoning with the city of Seneca for single family, multi-family, mixed commercial, commercial, etc., this Crescent land has never been zoned. The Lake Keowee interior acreage is close to town, shopping, dining, medical, Clemson University. Buyers to verify everything of importance.

76.66 acres Frontage Road and Knollwood Drive Road Unit Keowee Interior, Seneca
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“ Based on information submitted to the MLS GRID as of . All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Some IDX listings have been excluded from this website. Properties may or may not be listed by the office/agent presenting the information © 2026 Canopy MLS as distributed by MLS GRID”

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