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Seneca, SC Homes for Sale

Seneca sits between Lake Keowee and Lake Hartwell in Oconee County, which is the far western end of the Upstate and a genuinely different market from the I-85 corridor.

Retirees have driven a lot of the demand here for years — two lakes, mountains within reach, and pricing below what comparable water access costs almost anywhere else in the Southeast. Lake Keowee homes is the place to start if the water is the point.

On any lake property, confirm dock permitting and shoreline classification early; Keowee and Hartwell are managed differently and what you can build at the water varies by cove.

Recent Seneca Listings

$880,000
4 Beds 5 Baths 20299929 MLS
Home and 12 acres in a highly desired location just minutes from the new Target shopping center, medical support services, and historic Ram Cat Alley in Seneca. A private entrance with custom designed double gates flanked by illuminated stone pillars. Enjoy the view across a fenced front lawn on a quiet front porch or spend the day grilling and entertaining on one of two back decks overlooking the lush green pastures. This turnkey home of over 3300 finished square feet is a combination of the original 1985 build and a massive addition in 2016 to include 3 car garage. The original portion was fully renovated during that addition in 2016 to seamlessly match the new side. The crisp white kitchen features stainless appliances (Bosch & Frigidaire), granite center island, walk in pantry, convenient powder room and gleaming real hardwood flooring. An open dining area is large enough to seat 8 and opens to the comfortable living room with stone fireplace(gas logs). Main floor owner's suite has twin walk in closets, updated vanity and custom tiled walk in shower. A second bedroom on the main level has walk in closet and close access to a full bath on the hall. Do not miss the "secret" guest suite and bath with walk in shower, hidden above the living room at the top of the original hardwood staircase. The laundry room is a pet lover's dream complete with interior and exterior entrance doors, storm door has pet access, convenient walk in pet or utility shower tiled to match flooring, built in pet crate storage area (will fit two large crates or multiple small), granite counters with folding space, laundry sink, tiled flooring, and spacious cabinet storage. Follow the carpeted stairs to a second finished living area large enough for enjoying a crowd for the big game and a fourth bedroom with walk in closet and full bath. The grounds are plentiful in pecan and oak trees and the owner's personal favorite a tall red maple seen from the kitchen window. The property is ready for your horses and/or livestock with fencing and cross fencing, hay storage shed, multiple water taps, custom built "boutique" chicken house, potting shed, and a new shop building(2020) with two roll up doors, high ceiling, concrete flooring, 220 power and side entrance door.

111 N Grant Road, Seneca

$1,649,000
5 Beds 4 Baths 20300123 MLS
Rustic elegance meets luxury in this exceptional 2022 Lake Keowee waterfront log home in gated Harbor Point. Set on 1.55 acres, the property offers peaceful lake living minutes from shopping, with a wraparound porch, lighted concrete golf-cart path to a firepit overlooking your private cove, and a covered dock with power, water, underwater lighting and outdoor shower. The open-concept great room features vaulted ceilings, a stone gas fireplace with live-edge cedar mantel, Kolbe windows and wrought-iron railing details. The main-level kitchen is appointed with white granite, stainless appliances (gas range, convection/air-fryer oven), large island with under-counter microwave drawer and touchless gold faucet. The primary suite opens to the porch and includes two walk-in closets, dual vanities with touch-screen LED mirrors, soaking tub and tiled shower. Two additional main-level bedrooms share a luxe bath; main-floor laundry has a farm sink and granite counters. The terrace level offers a full second kitchen with icemaker, stained concrete floors, multi-slide doors, stone gas fireplace, two en-suite bedrooms, and a flexible room for a wine cellar or bunk room. Ample storage, large utility and pantry spaces, sliders from every bedroom to the covered patio, nearly level circular driveway and oversized 2-car garage complete the package. HOA permits guest houses and short-term rentals; community amenities include a waterside pavilion with outdoor kitchen and firepit plus RV/trailer storage. Quiet, protected cove ideal for swimming and fishing. This home can be purchased turn key (negotiable). Call for details.

1111 Little River View Drive, Seneca

$279,900
3 Beds 2 Baths 20300005 MLS
This charming, classic home tucked away on a small street close to Seneca's commercial corridor holds a lot of history and a lot of possibilities. From a spacious yard with multiple fenced areas, mature flowering bushes and trees, and numerous outbuildings, the options are almost endless. The detached garage has multiple entry and exit points, perfect for parking cars and keeping yard equipment. At the back of the yard sits a separate workshop, with 2 covered porches and plenty of room to work inside. A paved breezeway from the detached garage leads to the walk-in crawlspace with ample storage space below the house. At the front of the house is a covered porch wrapping from the living room entrance to the kitchen entrance. The front opens into an inviting living room with a gas fireplace and built-in shelving. Beyond the living room to the right lies the kitchen and eating area, with a laundry room leading to the backyard. The three bedrooms are situated at the left side of the house. The primary bedroom features an en-suite bathroom with a walk-in shower and tub. The second bathroom sits in the hall by the bedrooms for ease of access. The wooded surroundings of Jantzen Court give the feeling of a cozy small neighborhood, but the home is less than a minute from highway 123 and has immediate access to Seneca amenities such as shopping, groceries, and entertainment. The drive to Clemson is less than 20 minutes, traffic permitting. Property is in an estate. Please provide proof of funds or pre-approval with all offers. All numeric representations are estimates and are not guaranteed. Have the buyer take their own measurements if exact measurements are needed. Agents and buyers, please confirm the specifics of interior or exterior home features with a home inspector if need be. Please do not send “love letters,” as they may innocently contain personal information that reveals a prohibited basis for discrimination of a protected class (race, color, religion, national origin, sex, familial status, and disability). To protect fair housing laws and give all buyers equal opportunity, and to prevent a seller from a bias, we kindly ask all buyer agents to maintain best practices and only submit South Carolina approved documents or supplemental documents as provided and uploaded into the MLS.

21 Jantzen Court, Seneca

$279,900
3 Beds 2 Baths 1588536 MLS
This charming, classic home tucked away on a small street close to Seneca's commercial corridor holds a lot of history and a lot of possibilities. From a spacious yard with multiple fenced areas, mature flowering bushes and trees, and numerous outbuildings, the options are almost endless. The detached garage has multiple entry and exit points, perfect for parking cars and keeping yard equipment. At the back of the yard sits a separate workshop, with 2 covered porches and plenty of room to work inside. A paved breezeway from the detached garage leads to the walk-in crawlspace with ample storage space below the house. At the front of the house is a covered porch wrapping from the living room entrance to the kitchen entrance. The front opens into an inviting living room with a gas fireplace and built-in shelving. Beyond the living room to the right lies the kitchen and eating area, with a laundry room leading to the backyard. The three bedrooms are situated at the left side of the house. The primary bedroom features an en-suite bathroom with a walk-in shower and tub. The second bathroom sits in the hall by the bedrooms for ease of access. The wooded surroundings of Jantzen Court give the feeling of a cozy small neighborhood, but the home is less than a minute from highway 123 and has immediate access to Seneca amenities such as shopping, groceries, and entertainment. The drive to Clemson is less than 20 minutes, traffic permitting. Property is in an estate.

21 Jantzen Court, Seneca

$399,000
3 Beds 2 Baths 20299607 MLS
Situated at 125 and 135 Seneca River Rd in Seneca, SC, this unique 6.81-acre property offers an exceptional opportunity for investors, developers, entrepreneurs—and even families—seeking a versatile piece of land in a prime location. Just one mile from Lake Hartwell and less than three miles from Clemson University, the setting combines convenience, accessibility, and strong growth potential. The property features a gently sloping, mostly level landscape, making it ideal for a wide range of possibilities—from student housing and long- or short-term rentals to boat storage or other income-producing ventures. At the same time, it would make a wonderful homesite for a family looking to enjoy a spacious, beautiful property with close access to the lake for boating, fishing, and outdoor recreation. Included on the property is a 1,770-square-foot brick home built in 1979, complete with a full, unfinished basement. The structure offers solid construction and “great bones,” providing a strong foundation for renovation or repurposing. However, the home has never been updated and will require significant improvements. Exterior work is needed, including repairs or replacement of boxing, fascia boards, gutters, shingles, windows, and exterior trim painting. Inside, the home is ready for a full update, including kitchen and bathroom renovations, new flooring, and fresh paint throughout. Beyond the property itself, the location is a standout feature—offering convenient access to regional and international airports, as well as nearby mountains, lakes, rivers, hiking trails, and waterfalls. The area also provides easy access to major sporting events and the vibrant energy of a college town. Whether you’re looking to renovate, redevelop, build an investment portfolio, or create a private family retreat near the lake, this property presents a rare chance to capitalize on location, acreage, and potential all in one. This home will be sold in AS-IS condition.

135 Seneca River Road, Seneca

$334,900
3 Beds 2 Baths 20298910 MLS
New SS Range, New SS Dishwasher, New Luxury Flooring Installed August 21, 2026-See New Photos Added ! Welcome to 200 Leila Street in Seneca, South Carolina, a well maintained home that offers comfort, functionality, and a convenient location just minutes from Lake Keowee and Clemson University. Enough land on two lots to build a second home. This approximately 1,865 square foot home features three bedrooms and two full bathrooms with a thoughtful layout designed for everyday living. The spacious living room serves as the heart of the home, highlighted by a classic wood burning fireplace that creates a warm and inviting atmosphere for relaxing or entertaining. The kitchen is both practical and welcoming with durable tile countertops, modern appliances, and a cozy kitchenette area for casual meals. A separate formal dining room with beautiful full length windows allows natural light to fill the space, making it ideal for gatherings and special occasions. The primary suite offers a private retreat with a large walk in closet and an ensuite bathroom featuring both a soaking tub and separate shower. Two additional bedrooms share a comfortable full bath, providing flexibility for family, guests, or a home office. From the Den, step outside to enjoy the large covered back deck overlooking a fenced backyard that is easy to maintain and perfect for pets, outdoor dining, or quiet evenings at home. Situated on approximately two Lots 10 and 11, enough land to build a second home, the property provides a nice balance of open space and privacy. The laundry room is located next to the Den. The two garage has plenty of storage room. Conveniently located near shopping, dining, medical facilities, and outdoor recreation, this home offers easy access to Lake Keowee, Clemson University, and major routes throughout the Upstate. Close to everything ! Buyers to verify everything of importance ! This move in ready property is a great opportunity for buyers seeking comfort, space, and location in the growing Seneca area. The Architectural roof 3 years old, the Trane XL5i HVAC 5 years old and the Rheem water heater 1 year old per the seller. Offers Welcome ! NO HOA. House Qualifies For USDA Loan.

200 Leila Street, Seneca

$1,745,000
3 Beds 3 Baths 20299175 MLS
Your Lake Keowee dream home is here! 1408 Cool Ridge Drive in Seneca South Carolina was built in 2021. Situated on over an acre, this stunning waterfront property is perfectly positioned to maximize breathtaking lake views and year round enjoyment. Meticulously maintained, this home remains in like new condition and is exceptionally clean throughout. From the moment you step inside, you are welcomed by panoramic water views, vaulted ceilings, and beautiful wood beams that create the ultimate lakefront ambiance. The open concept design is ideal for entertaining, featuring warm natural finishes, a striking stone gas fireplace, and wide plank pine flooring throughout the main level. The chef’s kitchen is a showstopper with a 9 foot island, farmhouse sink, ample seating, stainless steel appliances, and a 6 burner gas cooktop. A convenient coffee station with a built in wine cooler ensures your favorite beverages are always within reach. The spacious primary suite offers private access to the screened porch along with serene lake views. The en suite bath features a large walk in shower, dual vanities, and a generous walk in closet. An additional bedroom and full bath are also located on the main level, along with a covered porch for relaxing outdoors. Above the garage, you will find an unfinished space perfect for walk in storage or future expansion. The fully finished lower level is designed for entertaining, featuring a large recreation room with custom live edge shelving and plenty of space for game day gatherings. A kitchenette with bar seating, sink, and refrigerator adds convenience. The lower level bedroom is comparable in size to the primary suite and includes direct access to the lower porch with lake views. This level also offers a full bath, flex room, and a bunk room with four twin beds and individual reading lights, perfect for hosting guests. Step outside to the back patio, where you will enjoy easy access to the gently sloping yard. Outdoor features include an outdoor shower, fire pit area, and a full size covered dock with bench seating and EZ steps. Located in a protected cove, the setting is ideal for swimming, kayaking, or simply floating with friends. Located in Harbor Point, one of the few communities on Lake Keowee that allows short term rentals, 1408 Cool Ridge Drive offers the perfect blend of luxury, comfort, and investment potential.

1408 Cool Ridge Drive, Seneca

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