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Land for Sale in Seneca, SC

Seneca sits in Oconee County with three lakes around it — Hartwell, Keowee and Jocassee — and the mountains rising behind them. Land here is largely a question of which water a parcel is near, and under whose rules.

  • Lake Keowee parcels, where Duke Energy governs the shoreline and dock permitting
  • Lake Hartwell parcels, where the Corps of Engineers does
  • Wooded mountain tracts north toward Walhalla, Salem and the Jocassee Gorges
  • Farm and pasture ground south and west, and homesites in town on public utilities

US-123 runs through Seneca toward Clemson and Easley, SC-130 climbs north toward Jocassee, and Oconee remains one of the least developed corners of the Upstate. Lake Keowee homes show what has already been built on the water.

Lots and Land Listings in Seneca

$389,900
20304750 MLS
This ±8.92-acre land parcel on Sheep Farm Road in Seneca, South Carolina represents a rare commercial development opportunity in one of the Upstate's most strategically positioned corridors. Situated directly adjacent to the Oconee Memorial Hospital campus, the site is ideally suited for medical office, outpatient services, retail, or professional uses seeking proximity to a major healthcare anchor and its associated patient and employee traffic. The property benefits from ±10,600 vehicles per day passing the frontage, an existing ±25' curb cut reducing near-term development costs, and Oconee County's Control Free District zoning, which provides broad flexibility for a wide range of commercial and institutional uses without the restrictions of traditional zoning overlays. For a hospital system, health network, or medical office developer, this site offers a direct adjacency to Oconee Memorial that is increasingly difficult to assemble — the corridor has limited remaining raw acreage of this size in immediate proximity to the hospital campus. The parcel is also well-suited for retail or service commercial uses capitalizing on the consistent traffic generated by the hospital, adjacent schools, and area residential growth. At $389,900, the pricing reflects strong value on a per-acre basis for a high-visibility, infrastructure-ready site in a healthcare corridor. Serious inquiries from owner-users, developers, and institutional buyers are welcome. Investment highlights ±8.92 Acres of commercial land with an existing ±25' curb cut directly off Sheep Farm Road Prime hospital corridor location — directly adjacent to the Oconee Memorial Hospital campus, one of the region's primary healthcare anchors High traffic exposure — ±10,600 VPD on Sheep Farm Road, with excellent visibility and access for retail, medical, or professional users Flexible use potential — suitable for medical office, retail, industrial, professional office, or future assemblage; no restrictive zoning in Oconee County's Control Free District allows broad development flexibility Existing infrastructure advantage — curb cut already in place, reducing entitlement timeline and site development costs Growth market — Seneca and Oconee County are experiencing sustained healthcare, residential, and commercial growth driven by Clemson University proximity and regional population expansion Assemblage opportunity — parcel size and shape lend themselves to adjacency plays with neighboring tracts for larger campus-style development

1 Sheep Farm Rd Road, Seneca

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